SCHEMBL385866

SCHEMBL385866

CN(C)Cc1cccn1C

nearest known ligand 0.61

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 2/20 0.46
CYP3A4 P08684 2/20 0.46
TRPM8 Q7Z2W7 1/20 0.40
ALDH1A1 P00352 3/20 0.40
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
CYP2D6 P10635 1/20 0.40
CYP2C19 P33261 1/20 0.40
HTR2A P28223 1/20 0.40
HTR2C P28335 1/20 0.40
HTR2B P41595 1/20 0.40
TSHR P16473 1/20 0.39
MAPT P10636 2/20 0.39
POLB P06746 1/20 0.38
RAB9A P51151 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
PKM P14618 1/20 0.38
TAAR1 Q96RJ0 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3973791 0.78 TRPM8 (0.44) HSD11B1CYP3A4TRPM8ALDH1A1MEN1
SCHEMBL16708778 0.78 HSD11B1 (0.44) HSD11B1CYP3A4TRPM8ALDH1A1MEN1
SCHEMBL2977082 0.77 CYP3A4 (0.47) CYP3A4ALDH1A1CYP2D6CYP2C19TSHR
SCHEMBL11967756 0.77 HSD11B1 (0.57) HSD11B1CYP3A4TRPM8ALDH1A1CYP2C19
Trimethylammonium SCHEMBL386754 0.76 CYP3A4 (0.39) HSD11B1CYP3A4ALDH1A1MEN1KMT2A
SCHEMBL10103709 0.75 MEN1 (0.44) CYP3A4ALDH1A1MEN1KMT2ACYP2D6
SCHEMBL386002 0.74 ALDH1A1 (0.37) ALDH1A1HTR2AHTR2CHTR2BTSHR
SCHEMBL11344641 0.74 HTR2C (0.35) HSD11B1CYP3A4ALDH1A1HTR2AHTR2C
SCHEMBL256678 0.73
SCHEMBL2979421 0.73 HRH3 (0.50) HSD11B1CYP3A4ALDH1A1KMT2ACYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250129115-A1 Methods Detecting Tertiary Amines and Compositions Related Thereto UNIV EMORY (US) 2025-04-24 US claimed
US-20250129115-A1 Methods Detecting Tertiary Amines and Compositions Related Thereto UNIV EMORY (US) 2025-04-24 US disclosed
US-9058915-B1 Omniconjugated conductive polymers and methods for making the same THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2015-06-16 US disclosed
US-9058915-B1 Omniconjugated conductive polymers and methods for making the same THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2015-06-16 US disclosed
US-8101650-B2 Method for treating a immunology-related disease DAIICHI SANKYO COMPANY, LIMITED (JP) 2012-01-24 US disclosed
US-8067396-B2 Amino alcohol compounds or phosphonic acid derivatives thereof SANKYO COMPANY, LIMITED (JP) 2011-11-29 US disclosed
US-7910617-B2 Method for suppressing the number of peripheral blood lymphocytes using an amino alcohol compound SANKYO COMPANY, LIMITED (JP) 2011-03-22 US disclosed
US-20100035842-A1 Amino alcohol compounds or phosphonic acid derivatives thereof SANKYO COMPANY, LIMITED (JP) 2010-02-11 US disclosed
US-20090326038-A1 Method for treating a immunology-related disease SANKYO COMPANY, LIMITED (JP) 2009-12-31 US disclosed
US-7638551-B2 Amino alcohol compounds or phosphonic acid derivatives thereof SANKYO COMPANY, LIMITED (JP) 2009-12-29 US disclosed
US-20070191468-A1 Amino alcohol compound DAIICHI SANKYO COMPANY, LIMITED (JP) 2007-08-16 US disclosed
EP-1806344-A1 OPTICALLY ACTIVE 4,4-DISUBSTITUTED OXAZOLIDINE DERIVATIVE AND METHOD FOR PRODUCING SAME Sankyo Company, Limited (JP) 2007-07-11 EP disclosed
EP-1806344-A1 OPTICALLY ACTIVE 4,4-DISUBSTITUTED OXAZOLIDINE DERIVATIVE AND METHOD FOR PRODUCING SAME Sankyo Company, Limited (JP) 2007-07-11 EP disclosed
US-20070142335-A1 Amino alcohol compounds or phosphonic acid derivatives thereof SANKYO COMPANY, LIMITED (JP) 2007-06-21 US disclosed
US-20070105933-A1 Amino alcohol compounds SANKYO COMPANY, LIMITED (JP) 2007-05-10 US disclosed
US-7199150-B2 Amino alcohol compounds SANKYO COMPANY, LIMITED (JP) 2007-04-03 US disclosed
EP-1733724-A1 AMINO ALCOHOL COMPOUND Sankyo Company, Limited (JP) 2006-12-20 EP disclosed
US-20050043386-A1 Amino alcohol derivatives or phosphonic acid derivatives and pharmaceutical compositions containing these SANKYO COMPANY, LIMITED (JP) 2005-02-24 US disclosed
EP-1471054-A1 AMINO ALCOHOL DERIVATIVE OR PHOSPHONIC ACID DERIVATIVE AND MEDICINAL COMPOSITION CONTAINING THESE Sankyo Company, Limited (JP) 2004-10-27 EP disclosed
US-4374256-A CONTROLLING THE RATE OF FEED OF THE QUATERNARY SALT TO HOT AQUEOUS ALKALI CYNIDE AND WATER-IMMISCIBLE SOLVENT ETHYL CORPORATION (US) 1983-02-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050043386-A1 Amino alcohol derivatives or phosphonic acid derivatives and pharmaceutical compositions containing these PHOSPHO1, CD4, FCGRT HSD11B1 442/4885CYP3A4 1492/4885TRPM8 4472/4885
US-20250129115-A1 Methods Detecting Tertiary Amines and Compositions Related Thereto DOT1L, SETDB1, PRMT3 HSD11B1 4871/4885CYP3A4 4755/4885TRPM8 3806/4885
US-20090326038-A1 Method for treating a immunology-related disease C3AR1, HRH3, HRH2 HSD11B1 328/4885CYP3A4 3443/4885TRPM8 2527/4885
US-20070105933-A1 Amino alcohol compounds ADH1C, C9, SSB HSD11B1 602/4885CYP3A4 1794/4885TRPM8 3438/4885
US-20070142335-A1 Amino alcohol compounds or phosphonic acid derivatives thereof HRH3, C3AR1, HRH4 HSD11B1 670/4885CYP3A4 3889/4885TRPM8 3469/4885
US-20070191468-A1 Amino alcohol compound ADH1A, ADH1C, BCAT1 HSD11B1 311/4885CYP3A4 75/4885TRPM8 3564/4885
US-20100035842-A1 Amino alcohol compounds or phosphonic acid derivatives thereof PHOSPHO1, ADH1C, ADH1A HSD11B1 897/4885CYP3A4 3301/4885TRPM8 4709/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.