Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | CA12 | O43570 | 6/20 | 0.44 |
| ▸ | CA9 | Q16790 | 5/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1120158 | 1.00 | CA2 (0.49) | CA2ALDH1A1KMT2ALMNACA12 | |
| SCHEMBL7915160 | 0.98 | LMNA (0.48) | CA2ALDH1A1KMT2ALMNACA12 | |
| SCHEMBL9007163 | 0.98 | LMNA (0.48) | CA2ALDH1A1KMT2ALMNACA12 | |
| SCHEMBL7901399 | 0.98 | LMNA (0.48) | CA2ALDH1A1KMT2ALMNACA12 | |
| SCHEMBL7901402 | 0.98 | LMNA (0.48) | CA2ALDH1A1KMT2ALMNACA12 | |
| SCHEMBL1880843 | 0.98 | LMNA (0.48) | CA2ALDH1A1KMT2ALMNACA12 | |
| SCHEMBL1880842 | 0.98 | LMNA (0.48) | CA2ALDH1A1KMT2ALMNACA12 | |
| SCHEMBL8084586 | 0.98 | LMNA (0.48) | CA2ALDH1A1KMT2ALMNACA12 | |
| SCHEMBL7915158 | 0.98 | LMNA (0.48) | CA2ALDH1A1KMT2ALMNACA12 | |
| SCHEMBL12391382 | 0.98 | LMNA (0.48) | CA2ALDH1A1KMT2ALMNACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2144919-B1 | MULTI STEP SYNTHESIS OF IBANDRONATE | HOFFMANN LA ROCHE (CH) | 2015-12-02 | — | — | EP | claimed |
| EP-1807090-B9 | PROCESS FOR THE PREPARATION OF IBANDRONATE | HOFFMANN LA ROCHE (CH) | 2011-11-09 | — | — | EP | claimed |
| EP-1807090-B1 | PROCESS FOR THE PREPARATION OF IBANDRONATE | HOFFMANN LA ROCHE (CH) | 2011-02-09 | — | — | EP | claimed |
| JP-2010523614-A | — | — | 2010-07-15 | — | — | JP | claimed |
| US-7662990-B2 | Process for preparing ibandronate | HOFFMANN-LA ROCHE INC. (US) | 2010-02-16 | — | — | US | claimed |
| EP-2144919-A2 | MULTI STEP SYNTHESIS OF IBANDRONATE | F. Hoffmann-Roche AG (CH) | 2010-01-20 | — | — | EP | claimed |
| WO-2008125483-A2 | MULTI STEP SYNTHESIS OF IBANDRONATE | F. HOFFMANN-LA ROCHE AG (CH) | 2008-10-23 | — | — | WO | claimed |
| US-20080255386-A1 | PROCESS FOR PREPARING IBANDRONATE | F. HOFFMAN-LA ROCHE AG (CH) | 2008-10-16 | — | — | US | claimed |
| EP-1807090-A2 | PROCESS FOR THE PREPARATION OF IBANDRONATE | F. Hoffmann-La Roche AG (CH) | 2007-07-18 | — | — | EP | claimed |
| US-7214818-B2 | Method for synthesizing bisphosphonate | HOFFMANN-LA ROCHE INC. (US) | 2007-05-08 | — | — | US | claimed |
| WO-2006045578-A2 | PROCESS FOR THE PREPARATION OF IBANDRONATE | F. HOFFMANN-LA ROCHE AG (CH) | 2006-05-04 | — | — | WO | claimed |
| US-20060094898-A1 | Method for synthesizing bisphosphonate | F. HOFFMANN-LA ROCHE AG (CH) | 2006-05-04 | — | — | US | claimed |
| US-9469715-B2 | Method for producing formaldehyde/CO2 copolymers | COVESTRO DEUTSCHLAND AG (DE) | 2016-10-18 | — | — | US | disclosed |
| EP-2144919-B1 | MULTI STEP SYNTHESIS OF IBANDRONATE | HOFFMANN LA ROCHE (CH) | 2015-12-02 | — | — | EP | disclosed |
| EP-2144919-B1 | MULTI STEP SYNTHESIS OF IBANDRONATE | HOFFMANN LA ROCHE (CH) | 2015-12-02 | — | — | EP | disclosed |
| US-20150337070-A1 | METHOD FOR PRODUCING FORMALDEHYDE/CO2 COPOLYMERS | BAYER MATERIALSCIENCE AG (DE) | 2015-11-26 | — | — | US | disclosed |
| WO-2006045578-A2 | PROCESS FOR THE PREPARATION OF IBANDRONATE | F. HOFFMANN-LA ROCHE AG (CH) | 2006-05-04 | — | — | WO | disclosed |
| US-20060094898-A1 | Method for synthesizing bisphosphonate | F. HOFFMANN-LA ROCHE AG (CH) | 2006-05-04 | — | — | US | disclosed |
| EP-0714885-B1 | Preparation process of aminoacetamide derivative | EISAI CO LTD (JP) | 1999-09-01 | — | — | EP | disclosed |
| EP-0714885-A2 | Preparation process of aminoacetamide derivative | EISAI CHEMICAL CO., LTD. (JP) | 1996-06-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060094898-A1 | Method for synthesizing bisphosphonate | BPGM, PHPT1, PPIP5K2 | CA2 566/4885ALDH1A1 1800/4885KMT2A 2945/4885 |
| US-20080255386-A1 | PROCESS FOR PREPARING IBANDRONATE | BPGM, MVD, PPIP5K2 | CA2 1484/4885ALDH1A1 1197/4885KMT2A 3429/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.