SCHEMBL7915158

SCHEMBL7915158

CCCCCC/N=C/c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.48
CA2 P00918 5/20 0.47
ALDH1A1 P00352 2/20 0.47
KMT2A Q03164 1/20 0.47
CA12 O43570 5/20 0.46
CA9 Q16790 4/20 0.46
TDP1 Q9NUW8 1/20 0.44
KDM4E B2RXH2 1/20 0.42
GAA P10253 1/20 0.42
MAPT P10636 1/20 0.42
TAAR1 Q96RJ0 1/20 0.42
EZH2 Q15910 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.41
CA1 P00915 1/20 0.41
EGFR P00533 1/20 0.41
CNR1 P21554 1/20 0.41
FAAH O00519 3/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8084586 1.00 LMNA (0.48) LMNACA2ALDH1A1KMT2ACA12
SCHEMBL12391382 1.00 LMNA (0.48) LMNACA2ALDH1A1KMT2ACA12
SCHEMBL7915160 1.00 LMNA (0.48) LMNACA2ALDH1A1KMT2ACA12
SCHEMBL7901399 1.00 LMNA (0.48) LMNACA2ALDH1A1KMT2ACA12
SCHEMBL9007163 1.00 LMNA (0.48) LMNACA2ALDH1A1KMT2ACA12
SCHEMBL7901402 1.00 LMNA (0.48) LMNACA2ALDH1A1KMT2ACA12
SCHEMBL1880843 1.00 LMNA (0.48) LMNACA2ALDH1A1KMT2ACA12
SCHEMBL1880842 1.00 LMNA (0.48) LMNACA2ALDH1A1KMT2ACA12
SCHEMBL1120158 0.98 CA2 (0.49) LMNACA2ALDH1A1KMT2ACA12
SCHEMBL1120157 0.98 CA2 (0.49) LMNACA2ALDH1A1KMT2ACA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230372915-A1 MANGANESE BASED COMPLEXES AND USES THEREOF FOR HOMOGENEOUS CATALYSIS YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2023-11-23 US disclosed
US-20230372915-A1 MANGANESE BASED COMPLEXES AND USES THEREOF FOR HOMOGENEOUS CATALYSIS YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2023-11-23 US disclosed
US-11731116-B2 Manganese based complexes and uses thereof for homogeneous catalysis YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2023-08-22 US disclosed
US-11731116-B2 Manganese based complexes and uses thereof for homogeneous catalysis YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2023-08-22 US disclosed
EP-3919466-A1 MANGANESE BASED COMPLEXES AND USES THEREOF FOR HOMOGENEOUS CATALYSIS Yeda Research and Development Co. Ltd (IL) 2021-12-08 EP disclosed
WO-2017137984-A1 MANGANESE BASED COMPLEXES AND USES THEREOF FOR HOMOGENEOUS CATALYSIS YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2017-08-17 WO disclosed
US-20170237119-A1 LI-ION ELECTROLYTE MEMBRANE FACILITATED BY A SELF-HEALING POLYMER MATRIX, AND ASSOCIATED BATTERY UNIV COLORADO REGENTS (US) 2017-08-17 US disclosed
US-20170237119-A1 LI-ION ELECTROLYTE MEMBRANE FACILITATED BY A SELF-HEALING POLYMER MATRIX, AND ASSOCIATED BATTERY UNIV COLORADO REGENTS (US) 2017-08-17 US disclosed
US-9453099-B2 Covalently cross-linked malleable polymers and methods of use THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) 2016-09-27 US disclosed
US-9453099-B2 Covalently cross-linked malleable polymers and methods of use THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) 2016-09-27 US disclosed
US-9328069-B2 Catalytic manufacturing method for imine having no substituent group on the nitrogen, and use for the imine produced POSTECH ACADEMY-INDUSTRY FOUNDATION (KR) 2016-05-03 US disclosed
US-9328069-B2 Catalytic manufacturing method for imine having no substituent group on the nitrogen, and use for the imine produced POSTECH ACADEMY-INDUSTRY FOUNDATION (KR) 2016-05-03 US disclosed
US-20150344428-A1 Catalytic Manufacturing Method for Imine Having No Substituent Group on the Nitrogen, and Use for the Imine Produced POSTECH ACADEMY-INDUSTRY FOUNDATION (KR) 2015-12-03 US disclosed
US-20150344428-A1 Catalytic Manufacturing Method for Imine Having No Substituent Group on the Nitrogen, and Use for the Imine Produced POSTECH ACADEMY-INDUSTRY FOUNDATION (KR) 2015-12-03 US disclosed
US-20150259458-A1 NOVEL COVALENTLY CROSS-LINKED MALLEABLE POLYMERS AND METHODS OF USE THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE 2015-09-17 US disclosed
US-20150259458-A1 NOVEL COVALENTLY CROSS-LINKED MALLEABLE POLYMERS AND METHODS OF USE THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE 2015-09-17 US disclosed
US-6200718-B1 A POLYMERIZED TONER OF CORE-SHELL STRUCTURE, COMPRISING CORE PARTICLES COMPOSED OF COLORED POLYMER PARTICLES WHICH CONTAIN A COMPOUND HAVING >C=N+ STRUCTURE IN ITS MOLECULE AND A COLORANT AND A LAYER OF POLYMER COVERING CORE PARTICLES NIPPON ZEON CO., LTD. (JP) 2001-03-13 US disclosed
EP-0947888-A1 POLYMER TONER AND METHOD OF PRODUCTION THEREOF NIPPON ZEON CO., LTD. (JP) 1999-10-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230372915-A1 MANGANESE BASED COMPLEXES AND USES THEREOF FOR HOMOGENEOUS CATALYSIS ADH1C, OTC, MLEC LMNA 1261/4885CA2 131/4885ALDH1A1 1959/4885
US-20150344428-A1 Catalytic Manufacturing Method for Imine Having No Substituent Group on the Nitrogen, and Use for the Imine Produced INMT, HNMT, NNMT LMNA 2490/4885CA2 1488/4885ALDH1A1 580/4885
US-11731116-B2 Manganese based complexes and uses thereof for homogeneous catalysis ADH1C, OTC, ADH5 LMNA 1251/4885CA2 169/4885ALDH1A1 2176/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.