Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT2B | Q92831 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TYR | P14679 | 1/20 | 0.30 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12763761 | 0.79 | SMN1; SMN2 (0.41) | SMN1; SMN2KMT2APDE4B | |
| SCHEMBL10480781 | 0.77 | TRPA1 (0.36) | SMN1; SMN2TRPA1KMT2A | |
| SCHEMBL7350683 | 0.76 | TSHR (0.35) | KAT2BTRPA1KDM4E | |
| Hydrochloric Acid SCHEMBL9248892 | 0.72 | LMNA (0.32) | — | |
| SCHEMBL17924830 | 0.67 | MGLL (0.44) | KAT2BSMN1; SMN2 | |
| SCHEMBL15785094 | 0.65 | ALDH1A1 (0.51) | KMT2AKDM4E | |
| SCHEMBL7296263 | 0.65 | ALDH1A1 (0.51) | KMT2AKDM4E | |
| SCHEMBL4681306 | 0.64 | FDPS (0.50) | — | |
| SCHEMBL10049650 | 0.64 | FGFR1 (0.56) | KAT2B | |
| SCHEMBL28287982 | 0.63 | KAT2B (0.42) | KAT2BTRPA1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0094149-A2 | Pharmaceutical compositions containing a complex of iron with N-substituted 3-hydroxypyrid-2-one or -4-one derivatives | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1983-11-16 | — | — | EP | claimed |
| EP-0093498-A2 | Pharmaceutical compositions containing N-substituted-3-hydroxypyrid-2-one or -4-one derivatives | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1983-11-09 | — | — | EP | claimed |