Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 5/20 | 0.60 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.60 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.60 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.60 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.60 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.60 |
| ▸ | HTR1D | P28221 | 1/20 | 0.58 |
| ▸ | HTR7 | P34969 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1741885 | 0.86 | ADRA2A (0.77) | ADRA2AADRA1AADRA2BADRA2CADRA1D | |
| SCHEMBL3169026 | 0.85 | ADRA2A (0.55) | ADRA2AADRA1AADRA2BADRA2CADRA1D | |
| SCHEMBL8020019 | 0.76 | ADRA2A (1.00) | ADRA2AADRA1AADRA2BADRA2CADRA1D | |
| SCHEMBL9220029 | 0.75 | MAPT (0.61) | ADRA2AADRA2BADRA2C | |
| SCHEMBL11198769 | 0.75 | ADRA2A (0.58) | ADRA2AADRA1AADRA2BADRA2CADRA1D | |
| SCHEMBL11199497 | 0.75 | NISCH (0.50) | ADRA2AADRA1AADRA2BADRA2CADRA1D | |
| SCHEMBL11591507 | 0.74 | ADRA2A (0.57) | ADRA2AADRA1AADRA2BADRA2CADRA1D | |
| SCHEMBL11513347 | 0.74 | ADRA2A (0.51) | ADRA2AADRA1AADRA2BADRA2CADRA1D | |
| SCHEMBL11187432 | 0.74 | ADRA2A (0.72) | ADRA2AADRA1AADRA2BADRA2CADRA1D | |
| SCHEMBL3670124 | 0.74 | WDR5 (0.48) | ADRA2AADRA1AADRA2BADRA2CADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0073960-A1 | 2-Arylhydrazino-2-imidazolines, their acyl derivatives, process for their preparation and their use in the control of endoparasites and ectoparasites | BAYER AG (DE) | 1983-03-16 | — | — | EP | disclosed |