SCHEMBL1741885

SCHEMBL1741885

Cc1cccc(NC2=NCCN2)c1C

nearest known ligand 0.77

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ADRA2A P08913 6/20 0.77
ADRA1A P35348 6/20 0.77
ADRA2B P18089 5/20 0.77
ADRA2C P18825 5/20 0.77
ADRA1D P25100 5/20 0.77
ADRA1B P35368 5/20 0.77
HTR1D P28221 1/20 0.69
HTR7 P34969 1/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8020019 0.87 ADRA2A (1.00) ADRA2AADRA1AADRA2BADRA2CADRA1D
SCHEMBL11203702 0.86 ADRA2A (0.60) ADRA2AADRA1AADRA2BADRA2CADRA1D
SCHEMBL11187432 0.84 ADRA2A (0.72) ADRA2AADRA1AADRA2BADRA2CADRA1D
SCHEMBL29412295 0.84 ADRA2A (0.65) ADRA2AADRA1AADRA2BADRA2CADRA1D
SCHEMBL29411887 0.84 ADRA2A (0.64) ADRA2AADRA1AADRA2BADRA2CADRA1D
SCHEMBL5612448 0.82 ADRA2A (0.61) ADRA2AADRA1AADRA2BADRA2CADRA1D
SCHEMBL4760243 0.81 HTR1D (1.00) ADRA2AADRA1AADRA2BADRA2CADRA1D
SCHEMBL11169014 0.81 ADRA1A (0.77) ADRA2AADRA1AADRA2BADRA2CADRA1D
Hydrochloric Acid SCHEMBL29384552 0.80 HTR1D (0.97) ADRA2AADRA1AADRA2BADRA2CADRA1D
SCHEMBL11160689 0.78 ADRA2A (0.71) ADRA2AADRA1AADRA2BADRA2CADRA1D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4180482-B1 MOISTURE-CURABLE COMPOSITION NITTO KASEI CO LTD (JP) 2025-12-03 EP disclosed
US-12479869-B2 Curing catalyst used for curing of polymer, method for producing same, moisture-curable composition, and method for producing cured product NITTO KASEI CO., LTD. (JP) 2025-11-25 US disclosed
EP-4174053-B1 CURING CATALYST USED FOR CURING OF POLYMER, METHOD FOR PRODUCING SAME, MOISTURE-CURABLE COMPOSITION, AND METHOD FOR PRODUCING CURED PRODUCT NITTO KASEI CO LTD (JP) 2025-11-19 EP disclosed
EP-4569023-A1 COMBINATION OF CATALYTIC COMPONENTS PolyU GmbH (DE) 2025-06-18 EP disclosed
CN-115516041-B Curing catalyst for curing polymer, method for producing same, moisture-curable composition, and method for producing cured product 日东化成株式会社 2024-06-28 CN disclosed
WO-2024033348-A1 COMBINATION OF CATALYTIC COMPONENTS POLYU GMBH (DE) 2024-02-15 WO disclosed
EP-4321573-A1 COMBINATION OF CATALYTIC COMPONENTS PolyU GmbH (DE) 2024-02-14 EP disclosed
US-20230234976-A1 CURING CATALYST USED FOR CURING OF POLYMER, METHOD FOR PRODUCING SAME, MOISTURE-CURABLE COMPOSITION, AND METHOD FOR PRODUCING CURED PRODUCT NITTO KASEI CO., LTD. (JP) 2023-07-27 US disclosed
EP-4180482-A1 MOISTURE-CURABLE COMPOSITION Nitto Kasei Co., Ltd. (JP) 2023-05-17 EP disclosed
EP-4174053-A1 CURING CATALYST USED FOR CURING OF POLYMER, METHOD FOR PRODUCING SAME, MOISTURE-CURABLE COMPOSITION, AND METHOD FOR PRODUCING CURED PRODUCT Nitto Kasei Co., Ltd. (JP) 2023-05-03 EP disclosed
US-20110237723-A1 CURABLE COMPOSITION AND CURED PRODUCT THEREOF KANEKA CORPORATION (JP) 2011-09-29 US disclosed
EP-2338938-A1 CURABLE COMPOSITION AND CURED PRODUCT THEREOF Kaneka Corporation (JP) 2011-06-29 EP disclosed
US-7960459-B2 Curable composition KANEKA CORPORATION (JP) 2011-06-14 US disclosed
EP-2267083-A1 CURABLE COMPOSITION AND CURED MATERIAL Kaneka Corporation (JP) 2010-12-29 EP disclosed
EP-1990371-B1 CURABLE COMPOSITION KANEKA CORP (JP) 2010-05-05 EP disclosed
US-20090209422-A1 Insecticidal Substituted Aminoalkyl Heterocyclic and Heteroaryl Derivatives BAYER CROPSCIENCE AG (DE) 2009-08-20 US disclosed
US-20090186993-A1 CURABLE COMPOSITION KANEKA CORPORATION (JP) 2009-07-23 US disclosed
EP-1990371-A1 CURABLE COMPOSITION Kaneka Corporation (JP) 2008-11-12 EP disclosed
EP-1879455-A1 INSECTICIDAL SUBSTITUTED AMINOALKYL HETEROCYCLIC AND HETEROARYL DERIVATIVES Bayer CropScience AG (DE) 2008-01-23 EP disclosed
WO-2006119411-A1 INSECTICIDAL SUBSTITUTED AMINOALKYL HETEROCYCLIC AND HETEROARYL DERIVATIVES BAYER CROPSCIENCE AG (DE) 2006-11-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12479869-B2 Curing catalyst used for curing of polymer, method for producing same, moisture-curable composition, and method for producing cured product KDM2B, SETDB1, ASH2L ADRA2A 3479/4885ADRA1A 3189/4885ADRA2B 1673/4885
US-20090209422-A1 Insecticidal Substituted Aminoalkyl Heterocyclic and Heteroaryl Derivatives DDT, AADAC, DDC ADRA2A 570/4885ADRA1A 799/4885ADRA2B 728/4885
US-20230234976-A1 CURING CATALYST USED FOR CURING OF POLYMER, METHOD FOR PRODUCING SAME, MOISTURE-CURABLE COMPOSITION, AND METHOD FOR PRODUCING CURED PRODUCT KDM2B, SETDB1, ASH2L ADRA2A 3479/4885ADRA1A 3189/4885ADRA2B 1673/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.