Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.32 |
| ▸ | PTPRC | P08575 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | GALR3 | O60755 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL973620 | 0.81 | LMNA (0.34) | ALDH1A1TDP1TSHRLMNAGPR35 | |
| SCHEMBL58486 | 0.79 | TSHR (0.46) | ALDH1A1TDP1TSHRLMNASMN1; SMN2 | |
| SCHEMBL261451 | 0.74 | TDP1 (0.45) | ALDH1A1TDP1TSHRLMNASMN1; SMN2 | |
| SCHEMBL207429 | 0.73 | CA2 (0.38) | ALDH1A1TDP1TSHR | |
| SCHEMBL10967569 | 0.72 | HTT (0.46) | ALDH1A1TDP1TSHRLMNASMN1; SMN2 | |
| SCHEMBL7949511 | 0.72 | GABRA1 (0.34) | ALDH1A1TDP1LMNASMN1; SMN2GPR35 | |
| SCHEMBL29213578 | 0.71 | CA2 (0.36) | — | |
| SCHEMBL27844049 | 0.71 | CA2 (0.36) | — | |
| SCHEMBL3317507 | 0.69 | ALDH1A1 (0.41) | ALDH1A1TDP1TSHRLMNAACHE | |
| SCHEMBL6310965 | 0.69 | TSHR (0.38) | ALDH1A1TDP1TSHRLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0075117-A2 | 2H-1,2,4,6-thiatriazine-1,1-dioxides, process for their preparation and their use as herbicides | BASF Aktiengesellschaft (DE) | 1983-03-30 | — | — | EP | disclosed |