SCHEMBL11204397

SCHEMBL11204397

Cc1nc2ccc3nc[nH]c3c2nc1C

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.44
PDPK1 O15530 2/20 0.37
PARP1 P09874 3/20 0.36
MAP3K5 Q99683 1/20 0.35
BRD4 O60885 1/20 0.33
CREBBP Q92793 1/20 0.33
MMP12 P39900 1/20 0.33
ADORA3 P0DMS8 1/20 0.33
ADORA1 P30542 1/20 0.33
CHEK1 O14757 1/20 0.33
PIM1 P11309 1/20 0.33
RPS6KA3 P51812 1/20 0.33
GDA Q9Y2T3 1/20 0.32
PRKCI P41743 1/20 0.32
KDM4E B2RXH2 1/20 0.32
RAD52 P43351 1/20 0.32
CSNK2A2 P19784 2/20 0.31
CSNK2A1 P68400 2/20 0.31
MEN1 O00255 1/20 0.31
RAB9A P51151 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11204399 0.76 MAPT (0.43) MAPTPARP1BRD4CREBBPMMP12
SCHEMBL11202171 0.73 MAPT (0.62) MAPTKDM4ERAB9A
SCHEMBL1374558 0.73 PRKCI (0.44) MAPTPDPK1PARP1MMP12CHEK1
SCHEMBL12438833 0.73 PARP1 (0.41) MAPTPARP1MMP12ADORA3PRKCI
SCHEMBL11203526 0.71 MAPT (0.46) MAPTPARP1ADORA3ADORA1KDM4E
SCHEMBL15834705 0.69 LMNA (0.44) MAPTPARP1MMP12PRKCIKDM4E
SCHEMBL30945080 0.69 ADRA2A (0.41) MAPTMMP12PRKCIKDM4ERAD52
SCHEMBL29503821 0.69 PARP1 (0.39) MAPTPDPK1PARP1BRD4CREBBP
SCHEMBL3156088 0.69 PARP1 (0.39) MAPTPDPK1PARP1BRD4CREBBP
SCHEMBL14438026 0.69 MAOA (0.39) MAPTPDPK1PARP1BRD4CREBBP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0014688-B1 PROCESS FOR THE TREATMENT OF SILVER DYE-BLEACHING MATERIALS, AQUEOUS PREPARATION THEREFOR, CONCENTRATE AND PROCESS FOR MAKING THE PREPARATION CIBA-GEIGY AG (CH) 1983-03-23 EP claimed
US-4304846-A USING MIXTURES OF A 1,4- OR 1,2-DIAZINE AS BLEACHING CATALYSTS; PREFERENTIAL REDOX POTENTIALS CIBA-GEIGY AG (CH) 1981-12-08 US claimed
EP-0014688-A2 Process for the treatment of silver dye-bleaching materials, aqueous preparation therefor, concentrate and process for making the preparation CIBA-GEIGY AG (CH) 1980-08-20 EP claimed
EP-0014688-B1 PROCESS FOR THE TREATMENT OF SILVER DYE-BLEACHING MATERIALS, AQUEOUS PREPARATION THEREFOR, CONCENTRATE AND PROCESS FOR MAKING THE PREPARATION CIBA-GEIGY AG (CH) 1983-03-23 EP disclosed
US-4304846-A USING MIXTURES OF A 1,4- OR 1,2-DIAZINE AS BLEACHING CATALYSTS; PREFERENTIAL REDOX POTENTIALS CIBA-GEIGY AG (CH) 1981-12-08 US disclosed
EP-0014688-A2 Process for the treatment of silver dye-bleaching materials, aqueous preparation therefor, concentrate and process for making the preparation CIBA-GEIGY AG (CH) 1980-08-20 EP disclosed