Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMS | P04818 | 7/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 7/20 | 0.42 |
| ▸ | BCL2 | P10415 | 6/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.37 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.35 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.35 |
| ▸ | TDP2 | O95551 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.35 |
| ▸ | XBP1 | P17861 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11204757 | 0.82 | KMT2A (0.44) | MCL1BCL2POLBKMT2AMEN1 | |
| SCHEMBL11206466 | 0.81 | KMT2A (0.41) | MCL1BCL2POLBKMT2AMEN1 | |
| SCHEMBL11558311 | 0.79 | HAO1 (0.36) | POLBHAO1TDP2 | |
| SCHEMBL3447724 | 0.78 | MAOA (0.43) | POLBHAO1ALDH1A1MAPTHTT | |
| SCHEMBL17726870 | 0.77 | MAPT (0.43) | TYMSMCL1BCL2POLBKMT2A | |
| SCHEMBL6937952 | 0.75 | TYMS (0.60) | TYMSMCL1BCL2POLBKMT2A | |
| SCHEMBL23430836 | 0.74 | MCL1 (0.56) | TYMSMCL1BCL2POLBKMT2A | |
| SCHEMBL11209931 | 0.74 | KMT2A (0.44) | MCL1BCL2POLBKMT2AMEN1 | |
| SCHEMBL16291732 | 0.73 | TYMS (0.53) | TYMSMCL1BCL2POLBKMT2A | |
| SCHEMBL12129683 | 0.72 | CYP1A2 (0.36) | TYMSPOLBKMT2AMEN1HAO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4151358-A | Ethynyl-substituted bis-naphthalimides | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 1979-04-24 | — | — | US | disclosed |
| US-4086248-A | Ethynyl-substituted aromatic anhydrides | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 1978-04-25 | — | — | US | disclosed |