Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.53 |
| ▸ | HTR7 | P34969 | 1/20 | 0.53 |
| ▸ | FAAH | O00519 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 3/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16826043 | 0.81 | HTR1A (0.54) | HTR1AHTR7FAAHGAAHRH3 | |
| SCHEMBL17289123 | 0.80 | FAAH (0.65) | HTR1AHTR7FAAHHRH3PTGDR2 | |
| SCHEMBL1331198 | 0.80 | FAAH (0.65) | HTR1AHTR7FAAHHRH3PTGDR2 | |
| SCHEMBL10856538 | 0.78 | GAA (0.58) | GAADRD4KDM4EALDH1A1LMNA | |
| SCHEMBL6584608 | 0.75 | FAAH (0.60) | HTR1AHTR7FAAHHRH3DRD4 | |
| SCHEMBL11202780 | 0.73 | POLB (0.56) | HTR1AHTR7DRD4KDM4EALDH1A1 | |
| SCHEMBL11196310 | 0.73 | KMT2A (0.52) | HTR7GAAKDM4EALDH1A1LMNA | |
| SCHEMBL23750987 | 0.73 | FAAH (0.55) | HTR1AHTR7FAAHHRH3PTGDR2 | |
| SCHEMBL11202213 | 0.73 | P2RX7 (0.43) | GAADRD4 | |
| SCHEMBL2170401 | 0.73 | CYP3A4 (0.55) | HTR1AHTR7FAAHDRD4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4421753-A | HYPOTENSIVE AGENTS | AMERICAN CYANAMID COMPANY (US) | 1983-12-20 | — | — | US | claimed |