Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 2/20 | 0.46 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 3/20 | 0.41 |
| ▸ | CES1 | P23141 | 3/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.40 |
| ▸ | IAPP | P10997 | 2/20 | 0.40 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.40 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.40 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.40 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.39 |
| ▸ | FEN1 | P39748 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL878984 | 0.83 | KEAP1 (0.56) | CYP4F2CYP4A11FFAR1 | |
| SCHEMBL7058525 | 0.82 | CTBP2 (0.50) | CYP4F2CYP4A11GAAALDH1A1ERCC5 | |
| SCHEMBL29966427 | 0.80 | AKR1B1 (0.55) | IAPP | |
| Potassium Ion SCHEMBL11450536 | 0.80 | CYP4F2 (0.46) | CYP4F2CYP4A11GAAGABRA1GABRB2 | |
| SCHEMBL9577316 | 0.79 | KDM4E (0.49) | CES2CES1GABRA1GABRB2ALDH1A1 | |
| SCHEMBL14434948 | 0.79 | IAPP (0.58) | CYP4F2CYP4A11GAAGABRA1GABRB2 | |
| SCHEMBL31284492 | 0.78 | PLAAT3 (0.60) | PLAAT3PLAAT5PLAAT2PLAAT4FFAR1 | |
| SCHEMBL9577381 | 0.78 | PLAAT3 (0.60) | PLAAT3PLAAT5PLAAT2PLAAT4FFAR1 | |
| SCHEMBL7637117 | 0.78 | MTNR1A (0.55) | ALDH1A1 | |
| Bicarbonate SCHEMBL29051241 | 0.78 | GABRA1 (0.55) | GAACES2CES1GABRA1GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0080822-A1 | Anti-hypertensive prolinol-based peptides | BEECHAM GROUP PLC (GB) | 1983-06-08 | — | — | EP | disclosed |