Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 known ✓ | P14867 | 1/20 | 0.40 |
| ▸ | GABRB2 known ✓ | P47870 | 1/20 | 0.40 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.46 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.44 |
| ▸ | IAPP | P10997 | 3/20 | 0.40 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11206999 | 0.80 | CYP4F2 (0.46) | CYP4F2CYP4A11GABRA1GABRB2IAPP | |
| SCHEMBL878984 | 0.79 | KEAP1 (0.56) | CYP4F2CYP4A11HDAC3HDAC1HDAC2 | |
| SCHEMBL14434948 | 0.79 | IAPP (0.58) | CYP4F2CYP4A11HDAC3HDAC1HDAC2 | |
| Potassium Ion SCHEMBL11272860 | 0.78 | HDAC3 (0.40) | CYP4F2CYP4A11HDAC3HDAC1HDAC2 | |
| SCHEMBL4601863 | 0.78 | CYP4F2 (0.47) | CYP4F2CYP4A11HDAC3HDAC1HDAC2 | |
| SCHEMBL4681231 | 0.78 | CYP4F2 (0.47) | CYP4F2CYP4A11HDAC3HDAC1HDAC2 | |
| SCHEMBL4681236 | 0.78 | CYP4F2 (0.47) | CYP4F2CYP4A11GABRA1GABRB2IAPP | |
| SCHEMBL6546730 | 0.75 | GABRA1 (0.50) | CYP4F2CYP4A11GABRA1GABRB2 | |
| SCHEMBL18802064 | 0.74 | CYP4F2 (0.57) | CYP4F2CYP4A11ALDH1A1LMNA | |
| SCHEMBL12086494 | 0.74 | CYP4F2 (0.45) | CYP4F2CYP4A11HDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4237039-A | Salts of arylalkanoic acids as corrosion inhibitors for poly(arylene sulfide)s | PHILLIPS PETROLEUM COMPANY (US) | 1980-12-02 | — | — | US | disclosed |