Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.50 |
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | STK17B | O94768 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11211029 | 0.87 | FAAH (0.41) | SLC6A3FAAH | |
| SCHEMBL11207790 | 0.85 | HTR1F (0.39) | SLC6A3FAAHHTR2ADRD3 | |
| Oxalic Acid SCHEMBL11210539 | 0.82 | HTR1F (0.38) | SLC6A3FAAHHTR2ADRD3 | |
| SCHEMBL11854426 | 0.73 | SLC6A3 (0.62) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL11855296 | 0.72 | SLC6A3 (0.61) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL3554782 | 0.71 | SLC6A3 (0.72) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL11210963 | 0.71 | HIF1A (0.52) | — | |
| SCHEMBL11932081 | 0.70 | SLC6A3 (0.55) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL11209018 | 0.69 | HIF1A (0.42) | — | |
| SCHEMBL12589285 | 0.68 | FAAH (0.46) | FAAHSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0094833-A2 | Novel 1,2-benzisoxazole derivatives | Dainippon Pharmaceutical Co., Ltd. (JP) | 1983-11-23 | — | — | EP | disclosed |