Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | HTR3A | P46098 | 2/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | PTGES | O14684 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.37 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11207375 | 0.87 | SLC6A3 (0.50) | FAAHSLC6A3 | |
| SCHEMBL11207790 | 0.83 | HTR1F (0.39) | FAAHHTR3ASLC6A3KMT2A | |
| SCHEMBL11210963 | 0.83 | HIF1A (0.52) | HIF1ANPC1RAB9AKMT2A | |
| Oxalic Acid SCHEMBL11210539 | 0.83 | HTR1F (0.38) | FAAHHTR3ASLC6A3KMT2A | |
| SCHEMBL9689288 | 0.76 | FAAH (0.46) | FAAHHIF1ANPC1RAB9AKMT2A | |
| SCHEMBL11857028 | 0.72 | CNR1 (0.49) | RAB9ASLC6A3 | |
| SCHEMBL11855303 | 0.70 | CNR1 (0.48) | RAB9ASLC6A3 | |
| SCHEMBL3953705 | 0.69 | NPC1 (0.48) | NPC1RAB9AEPHX1SLC6A3KMT2A | |
| SCHEMBL3953759 | 0.69 | NPC1 (0.48) | NPC1RAB9AEPHX1SLC6A3KMT2A | |
| SCHEMBL1565904 | 0.69 | MEN1 (0.47) | SLC6A3KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0094833-A2 | Novel 1,2-benzisoxazole derivatives | Dainippon Pharmaceutical Co., Ltd. (JP) | 1983-11-23 | — | — | EP | disclosed |