Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.44 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | PSMD10 | O75832 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8206287 | 0.92 | LMNA (0.46) | LMNASMN1; SMN2CHRM2CHRM1CHRM3 | |
| SCHEMBL18934283 | 0.90 | CYP19A1 (0.48) | ALDH1A1PSMD10CYP19A1 | |
| SCHEMBL18926558 | 0.85 | HTR6 (0.48) | SMN1; SMN2ALDH1A1TDP1PSMD10CYP19A1 | |
| SCHEMBL18926556 | 0.85 | CNR2 (0.48) | SMN1; SMN2ALDH1A1PSMD10CYP19A1 | |
| SCHEMBL8780822 | 0.84 | ALDH1A1 (0.44) | TAAR1ALDH1A1PSMD10CYP19A1 | |
| SCHEMBL8098377 | 0.84 | EGFR (0.49) | TAAR1ALDH1A1PSMD10CYP19A1 | |
| SCHEMBL8993345 | 0.83 | LMNA (0.50) | LMNASMN1; SMN2PGRALDH1A1MAPT | |
| SCHEMBL7723972 | 0.83 | CNR2 (0.54) | LMNAALDH1A1MAPTPSMD10TSHR | |
| SCHEMBL7028389 | 0.83 | CNR2 (0.50) | LMNAALDH1A1PSMD10 | |
| SCHEMBL4375489 | 0.83 | LMNA (0.43) | LMNASMN1; SMN2CHRM2CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0025192-B1 | SUBSTITUTED OXIRANE CARBOXYLIC ACIDS, PROCESS FOR THEIR PREPARATION, THEIR USE AND MEDICINES CONTAINING THEM | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1983-05-11 | — | — | EP | disclosed |
| EP-0025192-A2 | Substituted oxirane carboxylic acids, process for their preparation, their use and medicines containing them | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1981-03-18 | — | — | EP | disclosed |