Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.40 |
| ▸ | PSMD10 | O75832 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | CYP24A1 | Q07973 | 2/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.39 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.39 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7723991 | 0.92 | ALDH1A1 (0.46) | ALDH1A1PKMSLC6A3TAAR1CYP19A1 | |
| SCHEMBL18934283 | 0.90 | CYP19A1 (0.48) | ALDH1A1PSMD10CYP19A1CYP24A1FKBP1A | |
| SCHEMBL18926556 | 0.85 | CNR2 (0.48) | ALDH1A1PSMD10CYP19A1CYP24A1 | |
| SCHEMBL18926558 | 0.85 | HTR6 (0.48) | ALDH1A1PSMD10CYP19A1CYP24A1FKBP1A | |
| SCHEMBL11207479 | 0.84 | LMNA (0.44) | ALDH1A1TAAR1PSMD10CYP19A1 | |
| SCHEMBL8098377 | 0.84 | EGFR (0.49) | ALDH1A1TAAR1PSMD10CYP19A1CYP24A1 | |
| SCHEMBL1579408 | 0.84 | FFAR1 (0.47) | ALDH1A1TAAR1FDFT1 | |
| SCHEMBL776918 | 0.83 | ALDH1A1 (0.50) | ALDH1A1PKMCYP19A1 | |
| SCHEMBL4793354 | 0.83 | FKBP1A (0.52) | ALDH1A1PSMD10FKBP1A | |
| SCHEMBL7028389 | 0.83 | CNR2 (0.50) | ALDH1A1PSMD10CYP24A1FKBP1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0697407-B1 | Pyrimidinedione derivatives and antiarrhythmic compositions containing same | MITSUI TOATSU CHEMICALS (JP) | 1997-06-25 | — | — | EP | disclosed |
| EP-0697407-A1 | Pyrimidinedione derivatives and antiarrhythmic compositions containing same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-02-21 | — | — | EP | disclosed |