SCHEMBL11207644

SCHEMBL11207644

Cc1nc2ccc(NS(C)(=O)=O)cc2nc1C

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDC7 O00311 1/20 0.63
EEF2K O00418 1/20 0.63
PLK4 O00444 1/20 0.63
AURKA O14965 1/20 0.63
DYRK3 O43781 1/20 0.63
RPS6KA5 O75582 1/20 0.63
PRKD3 O94806 1/20 0.63
MAP4K4 O95819 1/20 0.63
PIM1 P11309 1/20 0.63
PHKG2 P15735 1/20 0.63
CDK2 P24941 1/20 0.63
AKT1 P31749 1/20 0.63
AKT2 P31751 1/20 0.63
MAPK8 P45983 1/20 0.63
MAPKAPK2 P49137 1/20 0.63
GSK3A P49840 1/20 0.63
GSK3B P49841 1/20 0.63
RPS6KA3 P51812 1/20 0.63
PRKX P51817 1/20 0.63
NEK2 P51955 1/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5696467 0.80 TP53 (0.57) CDC7EEF2KPLK4AURKADYRK3
SCHEMBL26352480 0.79 RAB9A (0.53) CYP1A2CYP3A4ALDH1A1KDM4EKMT2A
SCHEMBL9676236 0.77 NPC1 (0.51) CYP1A2ALDH1A1KDM4EKMT2AMET
SCHEMBL10951315 0.77 TERT (0.51) CDC7EEF2KPLK4AURKADYRK3
SCHEMBL5696511 0.77 TERT (0.51) CDC7EEF2KPLK4AURKADYRK3
SCHEMBL12076691 0.76 TP53 (0.62) CYP3A4CYP2C19ALDH1A1KDM4EKMT2A
SCHEMBL4665486 0.75 LMNA (0.68) ALDH1A1KDM4EKMT2AMAPTRAB9A
SCHEMBL8859238 0.75 RAB9A (0.56) CYP1A2CYP2C19ALDH1A1KDM4EKMT2A
SCHEMBL5338606 0.74 HSD11B1 (0.55) CDC7EEF2KPLK4AURKADYRK3
Iodide SCHEMBL10395553 0.74 RAB9A (0.55) CYP1A2CYP2C19ALDH1A1KDM4EKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0014688-B1 PROCESS FOR THE TREATMENT OF SILVER DYE-BLEACHING MATERIALS, AQUEOUS PREPARATION THEREFOR, CONCENTRATE AND PROCESS FOR MAKING THE PREPARATION CIBA-GEIGY AG (CH) 1983-03-23 EP claimed
US-4304846-A USING MIXTURES OF A 1,4- OR 1,2-DIAZINE AS BLEACHING CATALYSTS; PREFERENTIAL REDOX POTENTIALS CIBA-GEIGY AG (CH) 1981-12-08 US claimed
EP-0014688-A2 Process for the treatment of silver dye-bleaching materials, aqueous preparation therefor, concentrate and process for making the preparation CIBA-GEIGY AG (CH) 1980-08-20 EP claimed
EP-0014688-B1 PROCESS FOR THE TREATMENT OF SILVER DYE-BLEACHING MATERIALS, AQUEOUS PREPARATION THEREFOR, CONCENTRATE AND PROCESS FOR MAKING THE PREPARATION CIBA-GEIGY AG (CH) 1983-03-23 EP disclosed
US-4304846-A USING MIXTURES OF A 1,4- OR 1,2-DIAZINE AS BLEACHING CATALYSTS; PREFERENTIAL REDOX POTENTIALS CIBA-GEIGY AG (CH) 1981-12-08 US disclosed
EP-0014688-A2 Process for the treatment of silver dye-bleaching materials, aqueous preparation therefor, concentrate and process for making the preparation CIBA-GEIGY AG (CH) 1980-08-20 EP disclosed