Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11212389 | 0.89 | NPC1 (0.47) | IDH1NPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL2991545 | 0.83 | HTR7 (0.45) | IDH1NPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL7918609 | 0.82 | CALM1 (0.52) | IDH1NPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL9066733 | 0.78 | IDH1 (0.49) | IDH1SMN1; SMN2HPGDMAPK1CALM1 | |
| SCHEMBL31345536 | 0.78 | IDH1 (0.49) | IDH1SMN1; SMN2HPGDMAPK1CALM1 | |
| SCHEMBL29532678 | 0.76 | IDH1 (0.47) | IDH1NPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL146769 | 0.76 | IDH1 (0.47) | IDH1NPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL9719201 | 0.76 | IDH1 (0.47) | IDH1NPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL11201347 | 0.75 | PDCD1 (0.40) | IDH1NPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL218508 | 0.74 | TRPA1 (0.52) | NPC1RAB9ASMN1; SMN2POLBP2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4371726-A | Composition suitable for mechanical power transmission and process for operating traction drives | NIPPON STEEL CHEMICAL CO., LTD. (JP) | 1983-02-01 | — | — | US | disclosed |