Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11208647 | 0.90 | SGMS2 (0.48) | MAPTCYP1A2CYP3A4CYP2C19CYP2C9 | |
| SCHEMBL11279957 | 0.87 | RAB9A (0.44) | MAPTCYP1A2CYP3A4CYP2C19HPGD | |
| SCHEMBL11208145 | 0.80 | FFAR1 (0.46) | MAPTCYP1A2CYP3A4CYP2C19CYP2C9 | |
| SCHEMBL11282164 | 0.77 | PTPRZ1 (0.38) | MAPTCYP1A2CYP3A4CYP2C19HPGD | |
| SCHEMBL11208063 | 0.76 | FFAR1 (0.43) | MAPTALDH1A1SMN1; SMN2MAOB | |
| SCHEMBL11209448 | 0.71 | BCHE (0.48) | MAPTCYP1A2CYP3A4CYP2C19CYP2C9 | |
| SCHEMBL14410492 | 0.71 | GAA (0.69) | MAPTCYP1A2CYP3A4CYP2C19CYP2C9 | |
| SCHEMBL11209589 | 0.70 | TDP1 (0.50) | MAPTTP53NPSR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL11210926 | 0.69 | BCHE (0.52) | CYP1A2CYP2C19NPSR1SMN1; SMN2KMT2A | |
| SCHEMBL11211010 | 0.69 | HDAC3 (0.48) | CYP1A2CYP3A4CYP2C19CYP2C9GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0051196-B1 | 4-BENZYLOXY-ALPHA-TRICHLOROMETHYLBENZYL AMINES, PROCESS FOR THEIR PREPARATION, PESTICIDAL COMPOSITIONS CONTAINING THEM, THEIR PREPARATION AND USE | BAYER AG (DE) | 1983-11-09 | — | — | EP | disclosed |
| EP-0051196-A1 | 4-Benzyloxy-alpha-trichloromethylbenzyl amines, process for their preparation, pesticidal compositions containing them, their preparation and use | BAYER AG (DE) | 1982-05-12 | — | — | EP | disclosed |