Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM8 | O00222 | 1/20 | 0.44 |
| ▸ | GRM6 | O15303 | 1/20 | 0.44 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 3/20 | 0.41 |
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.41 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11208763 | 1.00 | GRM8 (0.44) | GRM8GRM6GRM4ALOX5MEN1 | |
| SCHEMBL8475304 | 0.90 | CES2 (0.47) | GRM8GRM6GRM4MEN1RAB9A | |
| SCHEMBL11208359 | 0.83 | ALOX5 (0.41) | ALOX5KMT2AACHETDP1L3MBTL1 | |
| SCHEMBL11204316 | 0.83 | ALOX5 (0.41) | ALOX5KMT2AACHETDP1L3MBTL1 | |
| SCHEMBL11206228 | 0.82 | GRIN2D (0.48) | MEN1KMT2AAOC3CYP1A2CYP2D6 | |
| SCHEMBL11211253 | 0.82 | GRIN2D (0.48) | MEN1KMT2AAOC3CYP1A2CYP2D6 | |
| SCHEMBL9662942 | 0.81 | NPSR1 (0.42) | GRM8GRM6GRM4MEN1RAB9A | |
| D-Alanine SCHEMBL11208761 | 0.80 | GRM8 (0.49) | GRM8GRM6GRM4ALOX5MEN1 | |
| Alanine SCHEMBL11205694 | 0.80 | GRM8 (0.49) | GRM8GRM6GRM4ALOX5MEN1 | |
| SCHEMBL14621033 | 0.80 | AOC3 (0.46) | GRM8GRM6GRM4ALOX5MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0009722-B1 | OPTICALLY ACTIVE COMPLEX, ALANINE.RING-SUBSTITUTED MANDELIC ACID, AND THE METHOD FOR PRODUCING THE SAME | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1983-03-02 | — | — | EP | claimed |
| EP-0009722-A1 | Optically active complex, alanine.Ring-substituted mandelic acid, and the method for producing the same | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1980-04-16 | — | — | EP | claimed |