Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2D | O15399 | 1/20 | 0.48 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.48 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.48 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.48 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.48 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.48 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11206228 | 1.00 | GRIN2D (0.48) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL11208359 | 0.85 | ALOX5 (0.41) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL11204316 | 0.85 | ALOX5 (0.41) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL9069627 | 0.83 | FFAR2 (0.42) | LMNAADRB2BRD4FFAR2L3MBTL1 | |
| SCHEMBL11208763 | 0.82 | GRM8 (0.44) | CYP2D6CYP2C19CYP1A2L3MBTL1MEN1 | |
| SCHEMBL11208244 | 0.82 | GRM8 (0.44) | CYP2D6CYP2C19CYP1A2L3MBTL1MEN1 | |
| SCHEMBL7733536 | 0.78 | CYP3A4 (0.55) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| Alanine SCHEMBL11206225 | 0.77 | LMNA (0.50) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| D-Alanine SCHEMBL11211250 | 0.77 | LMNA (0.50) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL21787636 | 0.77 | L3MBTL1 (0.50) | BRD4FFAR2L3MBTL1KMT2AHDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0009722-B1 | OPTICALLY ACTIVE COMPLEX, ALANINE.RING-SUBSTITUTED MANDELIC ACID, AND THE METHOD FOR PRODUCING THE SAME | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1983-03-02 | — | — | EP | claimed |
| EP-0009722-A1 | Optically active complex, alanine.Ring-substituted mandelic acid, and the method for producing the same | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1980-04-16 | — | — | EP | claimed |
| EP-0009722-A1 | Optically active complex, alanine.Ring-substituted mandelic acid, and the method for producing the same | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1980-04-16 | — | — | EP | disclosed |