Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | STAT3 | P40763 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.33 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11204316 | 1.00 | ALOX5 (0.41) | ALOX5KEAP1NFE2L2ACHELMNA | |
| SCHEMBL11211253 | 0.85 | GRIN2D (0.48) | LMNAADRB2KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL11206228 | 0.85 | GRIN2D (0.48) | LMNAADRB2KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL11208763 | 0.83 | GRM8 (0.44) | ALOX5ACHEKMT2AL3MBTL1TDP1 | |
| SCHEMBL11208244 | 0.83 | GRM8 (0.44) | ALOX5ACHEKMT2AL3MBTL1TDP1 | |
| SCHEMBL9663516 | 0.80 | LMNA (0.44) | ALOX5KEAP1NFE2L2ACHELMNA | |
| D-Alanine SCHEMBL11208357 | 0.77 | LMNA (0.52) | ALOX5KEAP1NFE2L2ACHELMNA | |
| Alanine SCHEMBL11209772 | 0.77 | LMNA (0.52) | ALOX5KEAP1NFE2L2ACHELMNA | |
| Alanine SCHEMBL11204313 | 0.77 | LMNA (0.52) | ALOX5KEAP1NFE2L2ACHELMNA | |
| D-Alanine SCHEMBL11207612 | 0.77 | LMNA (0.52) | ALOX5KEAP1NFE2L2ACHELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0009722-B1 | OPTICALLY ACTIVE COMPLEX, ALANINE.RING-SUBSTITUTED MANDELIC ACID, AND THE METHOD FOR PRODUCING THE SAME | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1983-03-02 | — | — | EP | claimed |
| EP-0009722-A1 | Optically active complex, alanine.Ring-substituted mandelic acid, and the method for producing the same | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1980-04-16 | — | — | EP | claimed |