Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 5/20 | 0.45 |
| ▸ | CA2 | P00918 | 5/20 | 0.45 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.44 |
| ▸ | ACP3 | P15309 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.44 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.44 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9662942 | 0.91 | NPSR1 (0.42) | CES2CES1NPSR1MEN1RAB9A | |
| SCHEMBL11208244 | 0.90 | GRM8 (0.44) | NPSR1MEN1RAB9AKMT2ACA1 | |
| SCHEMBL11208763 | 0.90 | GRM8 (0.44) | NPSR1MEN1RAB9AKMT2ACA1 | |
| SCHEMBL1533373 | 0.88 | RAB9A (0.50) | CES2CES1NPSR1MEN1RAB9A | |
| SCHEMBL1566713 | 0.88 | RAB9A (0.50) | CES2CES1NPSR1MEN1RAB9A | |
| SCHEMBL14621033 | 0.85 | AOC3 (0.46) | CES2CES1NPSR1MEN1RAB9A | |
| SCHEMBL7829230 | 0.83 | CASP1 (0.46) | NPSR1MEN1RAB9AKMT2AACP3 | |
| SCHEMBL11106829 | 0.83 | ALOX15 (0.54) | KMT2ACA1CA2AOC3ALOX15 | |
| SCHEMBL5319395 | 0.82 | CES2 (0.48) | CES2CES1NPSR1MEN1RAB9A | |
| SCHEMBL4634271 | 0.82 | TSHR (0.56) | CES2CES1NPSR1RAB9ACA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0929567-A1 | IMPROVED SOLID-PHASE PEPTIDE SYNTHESIS AND AGENT FOR USE IN SUCH SYNTHESIS | Zealand Pharmaceuticals A/S (DK) | 1999-07-21 | — | — | EP | claimed |
| WO-1998011125-A1 | IMPROVED SOLID-PHASE PEPTIDE SYNTHESIS AND AGENT FOR USE IN SUCH SYNTHESIS | ZEALAND PHARMACEUTICALS A/S (DK) | 1998-03-19 | — | — | WO | claimed |
| EP-0929567-A1 | IMPROVED SOLID-PHASE PEPTIDE SYNTHESIS AND AGENT FOR USE IN SUCH SYNTHESIS | Zealand Pharmaceuticals A/S (DK) | 1999-07-21 | — | — | EP | disclosed |
| WO-1998011125-A1 | IMPROVED SOLID-PHASE PEPTIDE SYNTHESIS AND AGENT FOR USE IN SUCH SYNTHESIS | ZEALAND PHARMACEUTICALS A/S (DK) | 1998-03-19 | — | — | WO | disclosed |