Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ESRRG | P62508 | 5/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | ESRRB | O95718 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11261351 | 0.84 | POLB (0.38) | LMNAMEN1KMT2AL3MBTL1 | |
| SCHEMBL11271674 | 0.83 | POLB (0.43) | LMNAEPHX2MEN1KMT2A | |
| SCHEMBL11265124 | 0.80 | ABCB11 (0.44) | LMNANPC1RAB9A | |
| SCHEMBL11208710 | 0.80 | LMNA (0.42) | LMNAESRRGNR1H4SIGMAR1S1PR1 | |
| SCHEMBL11261344 | 0.78 | TSHR (0.46) | LMNASIGMAR1 | |
| SCHEMBL11265051 | 0.75 | SMN1; SMN2 (0.51) | MEN1KMT2A | |
| SCHEMBL11272380 | 0.73 | LMNA (0.54) | LMNAMEN1KMT2AL3MBTL1 | |
| SCHEMBL11276195 | 0.73 | LMNA (0.57) | LMNAMEN1KMT2A | |
| SCHEMBL11296990 | 0.73 | LMNA (0.39) | LMNAMEN1KMT2A | |
| SCHEMBL11269559 | 0.73 | MAPT (0.43) | LMNANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4324796-A | HYPOGLYCEMIC AGENTS, HYPOKETONEMIC AGENTS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1982-04-13 | — | — | US | disclosed |