Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV3 | Q8NET8 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 5/20 | 0.38 |
| ▸ | DYRK2 | Q92630 | 5/20 | 0.38 |
| ▸ | CDK9 | P50750 | 1/20 | 0.38 |
| ▸ | LTB4R | Q15722 | 3/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | CLK1 | P49759 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11205319 | 0.83 | MEN1 (0.44) | TRPV3MEN1RAB9AKMT2ACNR2 | |
| SCHEMBL2301796 | 0.82 | MEN1 (0.54) | TRPV3MEN1RAB9AKMT2ACNR2 | |
| SCHEMBL11199852 | 0.79 | LTB4R (0.46) | TRPV3MEN1RAB9AKMT2ACNR2 | |
| SCHEMBL11204613 | 0.78 | CYP1A2 (0.53) | MEN1RAB9AKMT2ACNR2SLC6A2 | |
| SCHEMBL11202960 | 0.76 | CYP1A2 (0.39) | TRPV3MEN1RAB9AKMT2ASLC6A2 | |
| SCHEMBL11200300 | 0.76 | TSHR (0.54) | MEN1RAB9AKMT2ACNR2ADORA3 | |
| SCHEMBL22488586 | 0.76 | MAPT (0.36) | DYRK1ADYRK2CDK9 | |
| SCHEMBL11209392 | 0.75 | MEN1 (0.46) | TRPV3MEN1RAB9AKMT2ACNR2 | |
| SCHEMBL11208348 | 0.75 | KLK7 (0.44) | TRPV3MEN1RAB9AKMT2ACNR2 | |
| SCHEMBL11204151 | 0.73 | LTB4R (0.44) | TRPV3MEN1RAB9AKMT2ASLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0090353-A1 | 2-Pyridone derivatives, method for their preparation and pharmaceutical compositions containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-10-05 | — | — | EP | disclosed |