Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK7 | P49862 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | TACR3 | P29371 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TACR2 | P21452 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11204613 | 0.87 | CYP1A2 (0.53) | CNR2ADORA3ELANEMEN1KMT2A | |
| SCHEMBL11200300 | 0.86 | TSHR (0.54) | CNR2ADORA3MEN1KMT2ARAB9A | |
| SCHEMBL2301796 | 0.78 | MEN1 (0.54) | CNR2MEN1KMT2ARAB9AMAPT | |
| SCHEMBL11209392 | 0.75 | MEN1 (0.46) | CNR2ADORA3ELANEMEN1KMT2A | |
| SCHEMBL11208730 | 0.75 | TRPV3 (0.48) | CNR2ADORA3ELANEMEN1KMT2A | |
| SCHEMBL6641758 | 0.74 | SMN1; SMN2 (0.45) | MEN1KMT2ARAB9AALDH1A1KDM4E | |
| SCHEMBL11205319 | 0.74 | MEN1 (0.44) | CNR2ELANEMEN1KMT2ARAB9A | |
| SCHEMBL11199852 | 0.73 | LTB4R (0.46) | CNR2ADORA3ELANEMEN1KMT2A | |
| SCHEMBL1360819 | 0.72 | RAB9A (0.60) | ADORA3MEN1KMT2ARAB9ANR4A2 | |
| SCHEMBL11123099 | 0.72 | CYP1A2 (0.72) | KLK7MEN1KMT2AKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0090353-A1 | 2-Pyridone derivatives, method for their preparation and pharmaceutical compositions containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-10-05 | — | — | EP | disclosed |