Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 2/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.37 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.37 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2301796 | 0.82 | MEN1 (0.54) | MEN1KMT2ARAB9ASLC6A2SLC6A4 | |
| SCHEMBL11204613 | 0.78 | CYP1A2 (0.53) | MEN1KMT2ARAB9ASLC6A2SLC6A4 | |
| SCHEMBL11208730 | 0.75 | TRPV3 (0.48) | MEN1KMT2ARAB9ASLC6A2SLC6A4 | |
| SCHEMBL27645883 | 0.75 | MEN1 (0.54) | MEN1KMT2ARAB9ASLC6A2SLC6A4 | |
| SCHEMBL11208348 | 0.75 | KLK7 (0.44) | MEN1KMT2ARAB9ACNR2ELANE | |
| SCHEMBL11205319 | 0.74 | MEN1 (0.44) | MEN1KMT2ARAB9ASLC6A2SLC6A4 | |
| SCHEMBL11200300 | 0.73 | TSHR (0.54) | MEN1KMT2ARAB9ACNR2ADORA3 | |
| SCHEMBL1360819 | 0.72 | RAB9A (0.60) | MEN1KMT2ARAB9ASLC6A2SLC6A4 | |
| SCHEMBL5103779 | 0.72 | MEN1 (0.65) | MEN1KMT2ARAB9ASLC6A2SLC6A4 | |
| SCHEMBL3276265 | 0.72 | ALDH1A3 (0.42) | MEN1KMT2AALDH1A1TSHRATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0090353-A1 | 2-Pyridone derivatives, method for their preparation and pharmaceutical compositions containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-10-05 | — | — | EP | disclosed |