Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 14/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.38 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5331564 | 0.77 | SOAT1 (0.50) | LTB4RMEN1RAB9AKMT2A | |
| SCHEMBL2300904 | 0.76 | RAB9A (0.57) | MEN1RAB9AKMT2AHTR7SLC6A2 | |
| SCHEMBL11204150 | 0.76 | RAB9A (0.46) | LTB4RMEN1RAB9AKMT2AHTR7 | |
| SCHEMBL11205319 | 0.75 | MEN1 (0.44) | LTB4RMEN1RAB9AKMT2AHTR7 | |
| SCHEMBL28051936 | 0.73 | RAB9A (0.50) | LTB4RMEN1RAB9AKMT2AHTR7 | |
| SCHEMBL11208730 | 0.73 | TRPV3 (0.48) | LTB4RMEN1RAB9AKMT2AHTR7 | |
| SCHEMBL2301796 | 0.73 | MEN1 (0.54) | MEN1RAB9AKMT2ASLC6A2SLC6A4 | |
| SCHEMBL11204040 | 0.71 | LTB4R (0.71) | LTB4R | |
| SCHEMBL1360819 | 0.70 | RAB9A (0.60) | MEN1RAB9AKMT2ASLC6A2SLC6A4 | |
| SCHEMBL8987192 | 0.70 | LTB4R (0.71) | LTB4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0090353-A1 | 2-Pyridone derivatives, method for their preparation and pharmaceutical compositions containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-10-05 | — | — | EP | disclosed |