Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.44 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.44 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.44 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.44 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | PIM1 | P11309 | 9/20 | 0.40 |
| ▸ | PIM2 | Q9P1W9 | 8/20 | 0.40 |
| ▸ | PIM3 | Q86V86 | 5/20 | 0.40 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2523502 | 0.84 | KMT2A (0.42) | MEN1KMT2AGABRA1GABRG2GABRB3 | |
| SCHEMBL11204613 | 0.82 | CYP1A2 (0.53) | MEN1KMT2ARAB9AASIC3SLC6A2 | |
| SCHEMBL11208730 | 0.82 | TRPV3 (0.48) | MEN1KMT2ARAB9AASIC3SLC6A2 | |
| SCHEMBL11209392 | 0.82 | MEN1 (0.46) | MEN1KMT2ARAB9AASIC3GABRA1 | |
| SCHEMBL11205319 | 0.80 | MEN1 (0.44) | MEN1KMT2ARAB9AASIC3SLC6A2 | |
| SCHEMBL1360819 | 0.79 | RAB9A (0.60) | MEN1KMT2ARAB9AASIC3SLC6A2 | |
| SCHEMBL16334722 | 0.78 | FFAR4 (0.42) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL11208348 | 0.78 | KLK7 (0.44) | MEN1KMT2ARAB9ATRPV3MAPT | |
| SCHEMBL5103779 | 0.78 | MEN1 (0.65) | MEN1KMT2ARAB9AASIC3SLC6A2 | |
| SCHEMBL12093710 | 0.76 | KDR (0.43) | MEN1KMT2AMAPTATMCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8461183-B2 | PPAR agonist compounds, preparation and uses | GENFIT (FR) | 2013-06-11 | — | — | US | disclosed |
| US-20110195993-A1 | PPAR AGONIST COMPOUNDS, PREPARATION AND USES | GENFIT (FR) | 2011-08-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110195993-A1 | PPAR AGONIST COMPOUNDS, PREPARATION AND USES | PPARD, PPARA, PPARG | MEN1 4851/4885KMT2A 3347/4885RAB9A 2825/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.