Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10439916 | 0.81 | ACHE (0.35) | SMN1; SMN2TDP1GAAIDO1AGXT | |
| Pyridine SCHEMBL11257784 | 0.81 | — | — | |
| SCHEMBL11208304 | 0.78 | LMNA (0.36) | SLC6A2SLC6A4SLC6A3LMNACYP2A6 | |
| SCHEMBL11277499 | 0.78 | LMNA (0.36) | SLC6A2SLC6A4SLC6A3LMNACYP2A6 | |
| SCHEMBL10439950 | 0.78 | CYP3A4 (0.36) | TDP1ALDH1A1CYP3A4TSHRL3MBTL1 | |
| SCHEMBL11574256 | 0.77 | SLC6A2 (0.35) | SLC6A2SLC6A4SLC6A3LMNACYP2A6 | |
| SCHEMBL11451459 | 0.73 | ALDH1A3 (0.39) | LMNAKDM4ESMN1; SMN2ALDH1A1POLB | |
| SCHEMBL18434204 | 0.71 | IDO1 (0.39) | SLC6A2SLC6A4SLC6A3KDM4ESMN1; SMN2 | |
| SCHEMBL11208138 | 0.70 | LMNA (0.42) | SLC6A2SLC6A4SLC6A3LMNACYP2A6 | |
| SCHEMBL11604805 | 0.70 | LMNA (0.42) | SLC6A2SLC6A4SLC6A3LMNACYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0003897-B1 | PHOSPHINEGOLD(I)SALTS, PROCESS FOR THEIR PREPARATION AND COMPOSITIONS CONTAINING THEM | SMITHKLINE BECKMAN CORPORATION (US) | 1983-05-25 | — | — | EP | disclosed |
| EP-0003897-A1 | Phosphinegold(I)salts, process for their preparation and compositions containing them | SMITHKLINE BECKMAN CORPORATION (US) | 1979-09-05 | — | — | EP | disclosed |
| US-4096250-A | ANTI-ARTHRITIC | SMITHKLINE CORPORATION (US) | 1978-06-20 | — | — | US | disclosed |