SCHEMBL11277499

SCHEMBL11277499

CCOP(c1ccc(Cl)cc1)c1ccc(Cl)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.36
CYP2A6 P11509 1/20 0.36
SLC6A2 P23975 1/20 0.36
SLC6A4 P31645 1/20 0.36
SLC6A3 Q01959 1/20 0.36
SMN1; SMN2 Q16637 3/20 0.33
KDM4E B2RXH2 2/20 0.33
TDP1 Q9NUW8 2/20 0.33
ALDH1A1 P00352 2/20 0.33
POLB P06746 2/20 0.33
ABCB11 O95342 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
TSHR P16473 1/20 0.33
HTR2A P28223 1/20 0.33
PMP22 Q01453 1/20 0.33
PPARA Q07869 1/20 0.33
THRB P10828 1/20 0.33
HPGD P15428 1/20 0.33
KMT2A Q03164 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11208304 0.82 LMNA (0.36) LMNACYP2A6SLC6A2SLC6A4SLC6A3
SCHEMBL11574256 0.80 SLC6A2 (0.35) LMNACYP2A6SLC6A2SLC6A4SLC6A3
SCHEMBL10709571 0.79 ACHE (0.38) LMNACYP2A6SMN1; SMN2TDP1ALDH1A1
SCHEMBL11208853 0.78 SLC6A2 (0.34) LMNACYP2A6SLC6A2SLC6A4SLC6A3
SCHEMBL30356616 0.77 TP53 (0.39) LMNACYP2A6SMN1; SMN2TDP1ALDH1A1
SCHEMBL7778608 0.77 TDP1 (0.36) LMNASMN1; SMN2KDM4ETDP1POLB
SCHEMBL196443 0.76 CYP3A4 (0.39) TDP1ALDH1A1CYP3A4TSHR
SCHEMBL28449185 0.76 CA1 (0.48) KDM4ETDP1ALDH1A1CYP1A2CYP3A4
SCHEMBL31413753 0.75 CYP3A4 (0.36) ALDH1A1CYP3A4TSHRKMT2AGAA
SCHEMBL8638036 0.74 ALDH1A1 (0.46) CYP2A6SMN1; SMN2KDM4ETDP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117362338-A Method for preparing 3, 3-diaryl allyl substituted organic phosphonate compound 湖南理工学院 2024-01-09 CN claimed
CN-115925743-A Method for preparing (2-oxo-2-aryl ethyl) diaryl phosphine oxide compound 湖南理工学院 2023-04-07 CN claimed
CN-119504845-A Method for preparing S- (4- (2, 2-diaryl vinyl) thio-butyl) selenium/tellurium phosphorus/phosphonate 湖南理工学院 2025-02-25 CN disclosed
CN-117362338-A Method for preparing 3, 3-diaryl allyl substituted organic phosphonate compound 湖南理工学院 2024-01-09 CN disclosed
CN-115925743-A Method for preparing (2-oxo-2-aryl ethyl) diaryl phosphine oxide compound 湖南理工学院 2023-04-07 CN disclosed
US-4330461-A FIREPROOFING POLYESTERS AND POLYAMIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1982-05-18 US disclosed
US-4257973-A USING ORGANOPHOSPHORUS-PALLADIUM HALIDE COORDINATION CATALYST E. I. DU PONT DE NEMOURS AND COMPANY (US) 1981-03-24 US disclosed
US-4234729-A FIREPROOFING POLYMERS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1980-11-18 US disclosed
US-3966595-A REVERSE OSMOSIS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1976-06-29 US disclosed