Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11574256 | 0.98 | SLC6A2 (0.35) | LMNACYP2A6SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL11277499 | 0.82 | LMNA (0.36) | LMNACYP2A6SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8939012 | 0.82 | DRD2 (0.35) | SLC6A2SLC6A4SLC6A3SMN1; SMN2TDP1 | |
| Pyridine SCHEMBL11209411 | 0.79 | NPC1 (0.30) | KDM4ESMN1; SMN2ALDH1A1POLBTSHR | |
| SCHEMBL6867317 | 0.79 | ACHE (0.38) | CYP2A6SMN1; SMN2TDP1ALDH1A1CYP1A2 | |
| SCHEMBL11208853 | 0.78 | SLC6A2 (0.34) | LMNACYP2A6SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8939047 | 0.78 | SCN4A (0.35) | SLC6A2SLC6A4SLC6A3TDP1ABCB11 | |
| SCHEMBL11214200 | 0.77 | CYP2A6 (0.36) | LMNACYP2A6ALDH1A1HPGDGAA | |
| SCHEMBL911476 | 0.76 | CYP3A4 (0.39) | TDP1ALDH1A1CYP3A4TSHRMEN1 | |
| SCHEMBL8939010 | 0.76 | CA1 (0.48) | KDM4ETDP1ALDH1A1CYP3A4THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0003897-B1 | PHOSPHINEGOLD(I)SALTS, PROCESS FOR THEIR PREPARATION AND COMPOSITIONS CONTAINING THEM | SMITHKLINE BECKMAN CORPORATION (US) | 1983-05-25 | — | — | EP | disclosed |
| US-4096250-A | ANTI-ARTHRITIC | SMITHKLINE CORPORATION (US) | 1978-06-20 | — | — | US | disclosed |