Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR5A | P47898 | 6/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.35 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.35 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28871519 | 0.84 | CES2 (0.45) | HTR5AALDH1A1IDO1KDM4ENLRP3 | |
| SCHEMBL19960475 | 0.82 | EGFR (0.38) | HTR5AMAPTL3MBTL1ALDH1A1IDO1 | |
| SCHEMBL10952355 | 0.78 | BRD4 (0.40) | ALDH1A1BRD4CREBBPCA2 | |
| SCHEMBL11197568 | 0.77 | PARP1 (0.49) | HTR5AMAPTL3MBTL1ALDH1A1IDO1 | |
| SCHEMBL8233677 | 0.76 | PARP1 (0.38) | HTR5AMAPTL3MBTL1ALDH1A1IDO1 | |
| SCHEMBL15870042 | 0.76 | BRD4 (0.45) | HTR5AMAPTL3MBTL1ALDH1A1IDO1 | |
| SCHEMBL10957553 | 0.75 | CA2 (0.47) | HTR5AMAPTL3MBTL1ALDH1A1KDM4E | |
| SCHEMBL5119433 | 0.74 | HTR5A (0.47) | HTR5AL3MBTL1ALDH1A1BRD4CREBBP | |
| SCHEMBL4158156 | 0.73 | PGR (0.64) | — | |
| SCHEMBL10957521 | 0.73 | ALDH1A1 (0.41) | MAPTL3MBTL1ALDH1A1IDO1PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110204506-B | CO 2 Synthesis of 1,4-dihydro-2H-3,1-benzoxazine-2-one derivative as C1 source | 常州大学 | 2022-10-28 | — | — | CN | disclosed |
| EP-0093922-A2 | Benzoxazin-2-ones, their preparation and therapeutic agents containing these compounds | Dr. Karl Thomae GmbH (DE) | 1983-11-16 | — | — | EP | disclosed |