Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN4A | P35499 | 2/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | PPARA | Q07869 | 5/20 | 0.34 |
| ▸ | PPARG | P37231 | 4/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.34 |
| ▸ | HTR2A | P28223 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8939012 | 0.93 | DRD2 (0.35) | SCN4ADRD2DRD4DRD3LTA4H | |
| SCHEMBL8939051 | 0.88 | LTA4H (0.39) | LTA4HTDP1TSHRCYP3A4 | |
| SCHEMBL8939016 | 0.85 | DRD2 (0.36) | DRD2DRD4DRD3LTA4HPPARA | |
| SCHEMBL8939021 | 0.85 | CA4 (0.43) | DRD2DRD4DRD3LTA4H | |
| SCHEMBL8939002 | 0.80 | CA4 (0.47) | DRD2DRD4DRD3LTA4HKMT2A | |
| SCHEMBL11207316 | 0.78 | SCN4A (0.41) | SCN4ADRD2DRD4DRD3TDP1 | |
| SCHEMBL11208304 | 0.78 | LMNA (0.36) | TDP1PPARASLC6A4HTR2ACYP1A2 | |
| SCHEMBL911476 | 0.78 | CYP3A4 (0.39) | LTA4HTDP1TSHRCYP3A4KMT2A | |
| SCHEMBL11209353 | 0.76 | CYP3A4 (0.35) | LTA4HTDP1TSHRCYP3A4 | |
| SCHEMBL11701096 | 0.76 | TSHR (0.42) | SCN4ADRD2DRD4DRD3TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5498741-A | Alkyl aryl arylphosphonites, process for the preparation thereof and use thereof | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-03-12 | — | — | US | disclosed |