Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 2/20 | 0.45 |
| ▸ | RXRB | P28702 | 2/20 | 0.45 |
| ▸ | AHR | P35869 | 3/20 | 0.43 |
| ▸ | CHKA | P35790 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | APP | P05067 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11207670 | 0.83 | TSHR (0.48) | AHRTSHRLMNATP53HPGD | |
| SCHEMBL1958364 | 0.80 | RXRA (0.61) | RXRARXRBAHRCHKATSHR | |
| SCHEMBL5395302 | 0.80 | CHRNB2 (0.35) | TP53MAPK1TDP1 | |
| SCHEMBL18878428 | 0.79 | CNR1 (0.50) | RXRARXRBAHRCHKATSHR | |
| SCHEMBL6190849 | 0.75 | TSHR (0.50) | TSHRCNR1LMNATP53HPGD | |
| SCHEMBL4246853 | 0.75 | AHR (0.62) | RXRARXRBAHRCHKATSHR | |
| SCHEMBL4596500 | 0.73 | RXRA (0.50) | RXRARXRBAHRCHKATSHR | |
| SCHEMBL1764658 | 0.71 | ESR1 (0.32) | LMNATDP1PGRCYP1A2 | |
| SCHEMBL463754 | 0.71 | TSHR (0.73) | RXRARXRBAHRCHKATSHR | |
| SCHEMBL23560521 | 0.70 | CYP1A2 (0.65) | RXRARXRBAHRCHKATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0041672-B1 | PROCESS FOR THE PREPARATION OF AROMATIC ALDEHYDES | BAYER AG (DE) | 1983-09-28 | — | — | EP | disclosed |