Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | MYOC | Q99972 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.44 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | BCL9 | O00512 | 1/20 | 0.41 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9365950 | 0.82 | HTR2A (0.55) | MEN1KMT2ALMNAHTR2AMAPT | |
| SCHEMBL830301 | 0.82 | LMNA (0.56) | MEN1KMT2ALMNAHTR2AMAPT | |
| SCHEMBL11212430 | 0.81 | LMNA (0.43) | MEN1KMT2ALMNAMAPTMAPK1 | |
| SCHEMBL11207370 | 0.81 | EPHX2 (0.46) | MEN1KMT2AMAPTGAATDP1 | |
| SCHEMBL11249258 | 0.81 | ALDH1A1 (0.49) | MEN1KMT2ALMNAMAPTNPSR1 | |
| SCHEMBL655938 | 0.81 | MAPT (0.58) | MEN1KMT2ALMNAHTR2AMAPT | |
| SCHEMBL10872159 | 0.79 | MEN1 (0.56) | MEN1KMT2ALMNAHTR2AMAPT | |
| SCHEMBL831079 | 0.79 | LMNA (0.52) | MEN1KMT2ALMNAHTR2AMAPT | |
| SCHEMBL16261809 | 0.79 | LMNA (0.52) | MEN1KMT2ALMNAHTR2AMAPT | |
| Hydrochloric Acid SCHEMBL9362711 | 0.78 | MEN1 (0.54) | MEN1KMT2ALMNAHTR2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0030702-B1 | PROPIONIC-ACID ESTERS, PREPARATION OF THESE COMPOUNDS, HERBICIDES CONTAINING THEM AS ACTIVE INGREDIENTS, USE OF SUCH COMPOUNDS AND AGENTS AS HERBICIDES | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1983-08-24 | — | — | EP | disclosed |
| US-4329488-A | Propionic acid esters and herbicidal use thereof | HOFFMANN-LA ROCHE INC. (US) | 1982-05-11 | — | — | US | disclosed |
| EP-0030702-A1 | Propionic-acid esters, preparation of these compounds, herbicides containing them as active ingredients, use of such compounds and agents as herbicides | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1981-06-24 | — | — | EP | disclosed |