Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 3/20 | 0.43 |
| ▸ | PPARA | Q07869 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11209581 | 0.86 | FFAR1 (0.54) | CYP1A2CYP2C9CYP2C19L3MBTL1KMT2A | |
| SCHEMBL11249258 | 0.86 | ALDH1A1 (0.49) | L3MBTL1KMT2AMEN1MAPTPPARG | |
| SCHEMBL11212430 | 0.86 | LMNA (0.43) | L3MBTL1KMT2AMEN1MAPTGAA | |
| SCHEMBL10964710 | 0.84 | EPHX2 (0.62) | EPHX2CYP1A2CYP2C9CYP2C19L3MBTL1 | |
| SCHEMBL163796 | 0.82 | CYP1A2 (0.50) | EPHX2CYP1A2CYP2C9CYP2C19L3MBTL1 | |
| SCHEMBL11235870 | 0.82 | IDH1 (0.43) | L3MBTL1KMT2AMEN1PPARGPPARA | |
| SCHEMBL11209528 | 0.81 | MEN1 (0.48) | L3MBTL1KMT2AMEN1MAPTGAA | |
| SCHEMBL10968135 | 0.81 | L3MBTL1 (0.50) | EPHX2CYP1A2CYP2C9CYP2C19L3MBTL1 | |
| SCHEMBL9320809 | 0.80 | MEN1 (0.62) | EPHX2CYP1A2CYP2C9CYP2C19L3MBTL1 | |
| SCHEMBL9363151 | 0.80 | CYP1A2 (0.50) | EPHX2CYP1A2CYP2C9CYP2C19L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0030702-B1 | PROPIONIC-ACID ESTERS, PREPARATION OF THESE COMPOUNDS, HERBICIDES CONTAINING THEM AS ACTIVE INGREDIENTS, USE OF SUCH COMPOUNDS AND AGENTS AS HERBICIDES | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1983-08-24 | — | — | EP | disclosed |
| EP-0030702-A1 | Propionic-acid esters, preparation of these compounds, herbicides containing them as active ingredients, use of such compounds and agents as herbicides | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1981-06-24 | — | — | EP | disclosed |