Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | LDHA | P00338 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11249258 | 0.86 | ALDH1A1 (0.49) | LMNATDP1KMT2AGAAMEN1 | |
| SCHEMBL11207370 | 0.86 | EPHX2 (0.46) | TDP1KMT2AGAAMEN1L3MBTL1 | |
| SCHEMBL11158149 | 0.84 | LMNA (0.56) | LMNATDP1KMT2AGAAMEN1 | |
| SCHEMBL11235870 | 0.82 | IDH1 (0.43) | LMNAKMT2AMEN1L3MBTL1 | |
| SCHEMBL11209528 | 0.81 | MEN1 (0.48) | LMNATDP1KMT2AGAAMEN1 | |
| SCHEMBL11205887 | 0.80 | LMNA (0.40) | LMNATDP1KMT2AGAAMEN1 | |
| SCHEMBL11208999 | 0.79 | LMNA (0.42) | LMNATDP1KMT2AGAAMEN1 | |
| SCHEMBL31053227 | 0.79 | LMNA (0.60) | LMNATDP1KMT2AGAAMEN1 | |
| SCHEMBL10979352 | 0.79 | LMNA (0.60) | LMNATDP1KMT2AGAAMEN1 | |
| SCHEMBL10871441 | 0.77 | LDHA (0.59) | LMNATDP1GAALDHAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0030702-B1 | PROPIONIC-ACID ESTERS, PREPARATION OF THESE COMPOUNDS, HERBICIDES CONTAINING THEM AS ACTIVE INGREDIENTS, USE OF SUCH COMPOUNDS AND AGENTS AS HERBICIDES | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1983-08-24 | — | — | EP | disclosed |
| US-4329488-A | Propionic acid esters and herbicidal use thereof | HOFFMANN-LA ROCHE INC. (US) | 1982-05-11 | — | — | US | disclosed |
| EP-0030702-A1 | Propionic-acid esters, preparation of these compounds, herbicides containing them as active ingredients, use of such compounds and agents as herbicides | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1981-06-24 | — | — | EP | disclosed |