Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | FPR2 | P25090 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11212430 | 0.86 | LMNA (0.43) | ALDH1A1TDP1MAPTLMNASMN1; SMN2 | |
| SCHEMBL11207370 | 0.86 | EPHX2 (0.46) | TDP1MAPTL3MBTL1KMT2AGAA | |
| SCHEMBL11235870 | 0.85 | IDH1 (0.43) | LMNAL3MBTL1KMT2AFPR2SCN9A | |
| SCHEMBL10879122 | 0.84 | LMNA (0.56) | ALDH1A1TDP1MAPTLMNASMN1; SMN2 | |
| SCHEMBL11209528 | 0.81 | MEN1 (0.48) | TDP1MAPTLMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL8939660 | 0.80 | ALDH1A1 (0.59) | ALDH1A1TDP1MAPTLMNASMN1; SMN2 | |
| SCHEMBL3369250 | 0.79 | LMNA (0.60) | ALDH1A1TDP1MAPTLMNASMN1; SMN2 | |
| SCHEMBL2106687 | 0.79 | LMNA (0.60) | ALDH1A1TDP1MAPTLMNASMN1; SMN2 | |
| SCHEMBL10487619 | 0.79 | LMNA (0.60) | ALDH1A1TDP1MAPTLMNASMN1; SMN2 | |
| SCHEMBL11154253 | 0.77 | CYP1A2 (0.59) | ALDH1A1TDP1MAPTLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4329488-A | Propionic acid esters and herbicidal use thereof | HOFFMANN-LA ROCHE INC. (US) | 1982-05-11 | — | — | US | disclosed |
| EP-0030702-A1 | Propionic-acid esters, preparation of these compounds, herbicides containing them as active ingredients, use of such compounds and agents as herbicides | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1981-06-24 | — | — | EP | disclosed |