Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | RAD52 | P43351 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11199207 | 0.92 | ALDH1A1 (0.48) | DRD3ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL11204174 | 0.89 | ALDH1A1 (0.47) | DRD3ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL11203701 | 0.84 | HPGD (0.43) | ALDH1A1KDM4EHPGDHSD17B10LMNA | |
| SCHEMBL11204668 | 0.83 | PIM1 (0.40) | DRD3ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL11208613 | 0.80 | GAA (0.47) | DRD3ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL11205213 | 0.79 | PIM1 (0.42) | DRD3ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL11203471 | 0.73 | GPR84 (0.38) | ALDH1A1KDM4E | |
| SCHEMBL3474228 | 0.72 | ALDH1A1 (0.53) | DRD3ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL10925266 | 0.71 | DRD3 (0.61) | DRD3ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL10911793 | 0.68 | KCNH2 (0.41) | ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0090424-A1 | New quinolone compounds and preparation thereof | STERLING DRUG INC. (US) | 1983-10-05 | — | — | EP | disclosed |