Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.46 |
| ▸ | MEN1 | O00255 | 6/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | RAD52 | P43351 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11209760 | 0.89 | DRD3 (0.41) | ALDH1A1DRD3KDM4EMEN1KMT2A | |
| SCHEMBL11199207 | 0.89 | ALDH1A1 (0.48) | ALDH1A1DRD3KDM4EMEN1KMT2A | |
| SCHEMBL11203701 | 0.88 | HPGD (0.43) | ALDH1A1KDM4EMEN1KMT2AHPGD | |
| SCHEMBL11204668 | 0.87 | PIM1 (0.40) | ALDH1A1DRD3KDM4EMEN1KMT2A | |
| SCHEMBL11208613 | 0.86 | GAA (0.47) | ALDH1A1DRD3KDM4EMEN1KMT2A | |
| SCHEMBL11205213 | 0.83 | PIM1 (0.42) | ALDH1A1DRD3KDM4EHPGDLMNA | |
| SCHEMBL9379704 | 0.77 | ALDH1A1 (0.58) | ALDH1A1DRD3KDM4EMEN1KMT2A | |
| SCHEMBL11203471 | 0.77 | GPR84 (0.38) | ALDH1A1KDM4E | |
| SCHEMBL31025887 | 0.76 | ALDH1A1 (0.47) | ALDH1A1DRD3KDM4EMEN1KMT2A | |
| SCHEMBL7009049 | 0.74 | ALDH1A1 (0.42) | ALDH1A1DRD3KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0090424-A1 | New quinolone compounds and preparation thereof | STERLING DRUG INC. (US) | 1983-10-05 | — | — | EP | claimed |
| EP-0090424-A1 | New quinolone compounds and preparation thereof | STERLING DRUG INC. (US) | 1983-10-05 | — | — | EP | disclosed |