Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | RAD52 | P43351 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.45 |
| ▸ | HPGD | P15428 | 5/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11204174 | 0.86 | ALDH1A1 (0.47) | GAARAD52KDM4EALDH1A1HPGD | |
| SCHEMBL11209760 | 0.80 | DRD3 (0.41) | GAARAD52KDM4EALDH1A1HPGD | |
| SCHEMBL7015629 | 0.79 | KDM4E (0.41) | GAARAD52KDM4EALDH1A1HPGD | |
| SCHEMBL11199207 | 0.79 | ALDH1A1 (0.48) | GAARAD52KDM4EALDH1A1HPGD | |
| SCHEMBL11203701 | 0.75 | HPGD (0.43) | GAAKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL7011748 | 0.75 | ALOX5 (0.46) | GAAKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL7013585 | 0.74 | KDM4E (0.42) | GAARAD52KDM4EALDH1A1HPGD | |
| SCHEMBL11204668 | 0.74 | PIM1 (0.40) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL9523291 | 0.73 | KDM4E (0.51) | GAARAD52KDM4EALDH1A1HPGD | |
| SCHEMBL7020424 | 0.73 | ALOX5 (0.46) | GAAKDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0090424-A1 | New quinolone compounds and preparation thereof | STERLING DRUG INC. (US) | 1983-10-05 | — | — | EP | disclosed |