Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 2/20 | 0.40 |
| ▸ | GSK3A | P49840 | 2/20 | 0.40 |
| ▸ | GSK3B | P49841 | 2/20 | 0.40 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.40 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.40 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.40 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | CSNK1G3 | Q9Y6M4 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | LMNA | P02545 | 6/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | TOP2A | P11388 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11205213 | 0.94 | PIM1 (0.42) | PIM1GSK3AGSK3BPIM3PRKD3 | |
| SCHEMBL11204174 | 0.87 | ALDH1A1 (0.47) | ALDH1A1LMNAKDM4EHPGDHSD17B10 | |
| SCHEMBL11203701 | 0.86 | HPGD (0.43) | ALDH1A1LMNAKDM4EHPGDHSD17B10 | |
| SCHEMBL11199207 | 0.84 | ALDH1A1 (0.48) | ALDH1A1LMNAKDM4EHPGDHSD17B10 | |
| SCHEMBL11209760 | 0.83 | DRD3 (0.41) | ALDH1A1LMNAKDM4EHPGDHSD17B10 | |
| SCHEMBL11203471 | 0.75 | GPR84 (0.38) | ALDH1A1KDM4E | |
| SCHEMBL11208613 | 0.74 | GAA (0.47) | ALDH1A1KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL7557799 | 0.72 | ALDH1A1 (0.51) | PIM1GSK3AGSK3BPIM3PRKD3 | |
| SCHEMBL3474228 | 0.70 | ALDH1A1 (0.53) | ALDH1A1LMNAKDM4EHPGDHSD17B10 | |
| SCHEMBL9523388 | 0.70 | LMNA (0.64) | PIM1GSK3AGSK3BPIM3PRKD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0090424-A1 | New quinolone compounds and preparation thereof | STERLING DRUG INC. (US) | 1983-10-05 | — | — | EP | disclosed |