Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4639829 | 0.81 | TSHR (0.38) | ALDH1A1TSHRTHRB | |
| SCHEMBL9819877 | 0.80 | ALDH1A1 (0.38) | ALDH1A1TSHRTHRB | |
| SCHEMBL7022352 | 0.78 | TSHR (0.43) | ALDH1A1TSHRTHRB | |
| SCHEMBL332603 | 0.76 | TSHR (0.44) | ALDH1A1TSHRTHRBHSD17B10TDP1 | |
| SCHEMBL2407879 | 0.74 | ALDH1A1 (0.44) | ALDH1A1TSHRTHRBHSD17B10TDP1 | |
| SCHEMBL3446223 | 0.74 | ALDH1A1 (0.44) | ALDH1A1TSHRTHRBTDP1 | |
| SCHEMBL5672798 | 0.74 | ALDH1A1 (0.44) | ALDH1A1TSHRTHRBTDP1 | |
| SCHEMBL993470 | 0.74 | ALDH1A1 (0.44) | ALDH1A1TSHRTHRBTDP1 | |
| Ethylene Glycol SCHEMBL2384846 | 0.74 | ALDH1A1 (0.44) | ALDH1A1TSHRTHRBTDP1 | |
| SCHEMBL396934 | 0.73 | THRB (0.47) | ALDH1A1TSHRTHRBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4419505-A | HYDROXYSILYLALKYL (METH)ACRYLATE COPOLYMER | PARAGON OPTICAL, INC. (US) | 1983-12-06 | — | — | US | disclosed |