Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL35612 | 0.89 | TSHR (0.51) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL9301854 | 0.88 | TSHR (0.54) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL395578 | 0.88 | TSHR (0.50) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL396766 | 0.85 | THRB (0.47) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL9303996 | 0.85 | THRB (0.47) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL65596 | 0.85 | THRB (0.50) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL2369417 | 0.84 | THRB (0.51) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL12396078 | 0.84 | THRB (0.51) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL19239960 | 0.84 | TSHR (0.50) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL9764018 | 0.84 | TSHR (0.46) | THRBTSHRALDH1A1POLBAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11427666-B2 | Silicone-containing acrylic polymers for transdermal drug delivery compositions | NOVEN PHARMACEUTICALS, INC. (US) | 2022-08-30 | — | — | US | disclosed |
| US-10842787-B2 | Ophthalmic composition | Sydnexis, Inc. (US) | 2020-11-24 | — | — | US | disclosed |
| US-20200277424-A1 | SILICONE-CONTAINING ACRYLIC POLYMERS FOR TRANSDERMAL DRUG DELIVERY COMPOSITIONS | NOVEN PHARMACEUTICALS, INC. (US) | 2020-09-03 | — | — | US | disclosed |
| EP-3179989-B1 | SILICONE-CONTAINING ACRYLIC POLYMERS FOR TRANSDERMAL DRUG DELIVERY COMPOSITIONS | NOVEN PHARMA (US) | 2019-06-12 | — | — | EP | disclosed |
| US-20190091213-A1 | OPHTHALMIC COMPOSITION | NEWPORT RESEARCH, INC. | 2019-03-28 | — | — | US | disclosed |
| EP-3179989-A1 | SILICONE-CONTAINING ACRYLIC POLYMERS FOR TRANSDERMAL DRUG DELIVERY COMPOSITIONS | Noven Pharmaceuticals, INC. (US) | 2017-06-21 | — | — | EP | disclosed |
| WO-2016018858-A1 | SILICONE-CONTAINING ACRYLIC POLYMERS FOR TRANSDERMAL DRUG DELIVERY COMPOSITIONS | NOVEN PHARMACEUTICALS, INC. (US) | 2016-02-04 | — | — | WO | disclosed |
| US-20160030362-A1 | SILICONE-CONTAINING ACRYLIC POLYMERS FOR TRANSDERMAL DRUG DELIVERY COMPOSITIONS | NOVEN PHARMACEUTICALS, INC. (US) | 2016-02-04 | — | — | US | disclosed |
| US-8552085-B2 | Wettable silicone hydrogel contact lenses and related compositions and methods | COOPERVISION INTERNATIONAL HOLDING COMPANY, LP (BB) | 2013-10-08 | — | — | US | disclosed |
| US-20130031873-A1 | Wettable Silicone Hydrogel Contact Lenses And Related Compositions And Methods | COOPERVISION INTERNATIONAL HOLDING COMPANY, LP (BB) | 2013-02-07 | — | — | US | disclosed |
| US-8110697-B2 | Method for the production of polymerizable silicones | WACKER CHEMIE AG (DE) | 2012-02-07 | — | — | US | disclosed |
| US-8101789-B2 | Method for the production of polymerizable silicones | WACKER CHEMIE AG (DE) | 2012-01-24 | — | — | US | disclosed |
| EP-2125833-B1 | METHOD FOR THE PRODUCTION OF POLYMERISABLE SILICONES | WACKER CHEMIE AG (DE) | 2010-08-25 | — | — | EP | disclosed |
| EP-2125834-B1 | METHOD FOR THE PRODUCTION OF POLYMERISABLE SILICONES | WACKER CHEMIE AG (DE) | 2010-08-25 | — | — | EP | disclosed |
| US-20100041909-A1 | METHOD FOR THE PRODUCTION OF POLYMERIZABLE SILICONES | WACKER CHEMIE AG (DE) | 2010-02-18 | — | — | US | disclosed |
| US-20100029972-A1 | METHOD FOR THE PRODUCTION OF POLYMERIZABLE SILICONES | WACKER CHEMIE AG (DE) | 2010-02-04 | — | — | US | disclosed |
| US-5376378-A | Transdermal drug delivery | CIBA-GEIGY CORP. (US) | 1994-12-27 | — | — | US | disclosed |
| EP-0611783-A1 | Copolymers of (meth)acryloxy-alkyl-siloxysilane and alkyl(meth)acrylates and the use thereof as pressure sensitive adhesives | CIBA-GEIGY AG (CH) | 1994-08-24 | — | — | EP | disclosed |
| US-5288827-A | Drug selivery | CIBA-GEIGY CORPORATION (US) | 1994-02-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10842787-B2 | Ophthalmic composition | MYOC, PDE6H, PDE6C | THRB 3045/4885TSHR 2922/4885ALDH1A1 1319/4885 |
| US-20190091213-A1 | OPHTHALMIC COMPOSITION | MYOC, PDE6H, PDE6C | THRB 3045/4885TSHR 2922/4885ALDH1A1 1319/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.