SCHEMBL11210107

SCHEMBL11210107

COc1ccc(C(O)c2cc(C(C)(C)C)c(O)c(N)c2O)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.45
CA2 P00918 1/20 0.45
CYP3A4 P08684 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
LMNA P02545 1/20 0.39
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
AOC3 Q16853 2/20 0.36
ALDH1A1 P00352 3/20 0.35
NPSR1 Q6W5P4 1/20 0.35
GAA P10253 1/20 0.35
ALOX5 P09917 1/20 0.34
TSHR P16473 1/20 0.34
MAPK1 P28482 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
ELANE P08246 1/20 0.34
SCN1A P35498 1/20 0.34
SCN2A Q99250 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11214911 0.85 CA1 (0.44) CA1CA2CYP3A4CYP2C9CYP2C19
SCHEMBL11210116 0.85 PTGS1 (0.42) CA1CA2CYP3A4CYP2C9CYP2C19
SCHEMBL11219215 0.83 CA2 (0.33) CA1CA2CYP3A4CYP2C9CYP2C19
SCHEMBL11214177 0.83 TSHR (0.47) CA1CA2CYP3A4CYP2C9CYP2C19
SCHEMBL11214405 0.81 LMNA (0.43) CYP3A4CYP2C9CYP2C19LMNAMEN1
SCHEMBL11216880 0.81 KMT2A (0.43) CYP3A4CYP2C9CYP2C19LMNAMEN1
SCHEMBL30709677 0.80 CA2 (0.58) CA1CA2CYP3A4CYP2C9CYP2C19
SCHEMBL11298371 0.78 CYP3A4 (0.43) CA1CA2CYP3A4CYP2C9CYP2C19
SCHEMBL11215125 0.76 ALDH1A1 (0.41) CA1CA2CYP3A4CYP2C9CYP2C19
SCHEMBL11208331 0.73 PTGS1 (0.39) CA1CA2CYP3A4CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0079141-A1 Aminoresorcinol derivatives ONO PHARMACEUTICAL CO., LTD. (JP) 1983-05-18 EP disclosed