Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 1/20 | 0.44 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.40 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.40 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.40 |
| ▸ | ALB | P02768 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | RARB | P10826 | 1/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18970416 | 0.87 | CRHBP (0.41) | CRHBPCRHR2SIGMAR1 | |
| SCHEMBL18970326 | 0.85 | ITGB1 (0.48) | ALOX5KMT2ASIGMAR1LMNA | |
| SCHEMBL8221546 | 0.82 | TP53 (0.42) | SIGMAR1 | |
| SCHEMBL18970382 | 0.82 | SENP1 (0.50) | KMT2AMEN1 | |
| SCHEMBL18039236 | 0.81 | CRHBP (0.47) | CRHBPCRHR2KMT2AL3MBTL1SIGMAR1 | |
| SCHEMBL13951549 | 0.81 | HSD17B1 (0.46) | KMT2AMEN1LMNA | |
| SCHEMBL16274690 | 0.80 | CRHBP (0.46) | CRHBPCRHR2KMT2AL3MBTL1SIGMAR1 | |
| SCHEMBL4515187 | 0.80 | CRHBP (0.50) | CRHBPCRHR2HPGDKMT2AL3MBTL1 | |
| SCHEMBL13154972 | 0.79 | ALDH1A1 (0.45) | KMT2AL3MBTL1SIGMAR1TSHR | |
| SCHEMBL11465967 | 0.79 | RAB9A (0.40) | CRHBPCRHR2ALOX5L3MBTL1PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4405614-A | INSECTICIDES, MITICIDES, NEMATOCIDES | BASF AKTIENGESELLSCHAFT (DE) | 1983-09-20 | — | — | US | disclosed |