Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 8/20 | 0.53 |
| ▸ | HRH1 | P35367 | 3/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | HTR2C | P28335 | 4/20 | 0.38 |
| ▸ | RET | P07949 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7405300 | 0.89 | HTR2A (0.50) | HTR2AHRH1SLC6A2SLC6A4CYP2D6 | |
| SCHEMBL7270702 | 0.83 | OPRM1 (0.40) | HTR2AHRH1SLC6A2SLC6A4CYP2D6 | |
| SCHEMBL1702059 | 0.83 | HTT (0.46) | HTR2AHRH1SLC6A2SLC6A4CYP2D6 | |
| SCHEMBL7271568 | 0.83 | HTT (0.36) | HTR2AHRH1SLC6A2SLC6A4CYP2D6 | |
| SCHEMBL6790140 | 0.82 | ADRA2A (0.53) | HTR2AHRH1SLC6A2SLC6A4CYP2D6 | |
| SCHEMBL5497052 | 0.81 | HTT (0.45) | HTR2ASLC6A2SLC6A4CYP2D6HTR2C | |
| SCHEMBL9683908 | 0.74 | LMNA (0.40) | SLC6A2SLC6A4CYP2D6ADRA2AADRA2B | |
| SCHEMBL17193849 | 0.74 | LMNA (0.40) | SLC6A2SLC6A4CYP2D6ADRA2AADRA2B | |
| SCHEMBL7271833 | 0.74 | SLC6A2 (0.37) | HTR2AHRH1SLC6A2SLC6A4CYP2D6 | |
| SCHEMBL28758384 | 0.74 | SLC6A2 (0.40) | SLC6A2SLC6A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4417052-A | ANTIINFLAMMATORY AGENTS; ANALGESICS; VIRICIDES | STERLING DRUG INC. (US) | 1983-11-22 | — | — | US | disclosed |
| US-4308382-A | ANTIINFLAMMATORY AGENTS | STERLING DRUG INC. (US) | 1981-12-29 | — | — | US | disclosed |
| US-4216326-A | Intermediates for preparing anti-inflammatory phenyl-lower-alkylamines | STERLING DRUG INC. (US) | 1980-08-05 | — | — | US | disclosed |
| US-4080380-A | 2-Naphthyl-lower-alkylamines | STERLING DRUG INC. (US) | 1978-03-21 | — | — | US | disclosed |
| US-4069256-A | Anti-inflammatory phenyl-lower-alkylamines | STERLING DRUG INC. (US) | 1978-01-17 | — | — | US | disclosed |
| US-4028366-A | ANTIINFLAMMATORY AGENTS | STERLING DRUG INC. (US) | 1977-06-07 | — | — | US | disclosed |
| US-4008276-A | ANTIINFLAMMATORY | STERLING DRUG INC. (US) | 1977-02-15 | — | — | US | disclosed |
| US-4005093-A | ANTI-INFLAMMATORY AGENTS | STERLING DRUG INC. (US) | 1977-01-25 | — | — | US | disclosed |
| US-3965105-A | ANTIINFLAMMATORY | STERLING DRUG INC. (US) | 1976-06-22 | — | — | US | disclosed |