Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | EDNRA | P25101 | 3/20 | 0.41 |
| ▸ | EDNRB | P24530 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2967633 | 0.85 | GABRA1 (0.46) | GABRA1GABRB2CYP3A4MAPK1EDNRA | |
| SCHEMBL11220525 | 0.83 | MAOA (0.38) | EDNRAMAPTMAOBMEN1KMT2A | |
| SCHEMBL11342705 | 0.78 | EDNRA (0.42) | GABRA1GABRB2CYP3A4MAPK1EDNRA | |
| SCHEMBL26977072 | 0.73 | CYP19A1 (0.42) | CYP3A4EDNRAEDNRBMAPTNPC1 | |
| SCHEMBL10367170 | 0.73 | MAOB (0.48) | CYP3A4MAPTNPC1RAB9AMAOB | |
| SCHEMBL10694325 | 0.72 | EDNRA (0.49) | GABRA1GABRB2EDNRAEDNRBMAPT | |
| SCHEMBL10694317 | 0.72 | EDNRA (0.49) | GABRA1GABRB2EDNRAEDNRBMAPT | |
| SCHEMBL10694322 | 0.72 | EDNRA (0.49) | GABRA1GABRB2EDNRAEDNRBMAPT | |
| SCHEMBL11403457 | 0.72 | MAOB (0.39) | CYP3A4MAOBMEN1POLBKMT2A | |
| SCHEMBL29424037 | 0.70 | GABRA1 (0.48) | GABRA1GABRB2CYP3A4MAPK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4334067-A | ANTICONVULASANTS, ANTIULCER AGENTS | MARUKO SEIYAKU CO., LTD. (JP) | 1982-06-08 | — | — | US | disclosed |