Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MT-CO2 | P00403 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA3 | P07451 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA6 | P23280 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL490924 | 0.89 | PKM (0.48) | MT-CO2PTGS2PTGS1PKMKDM4E | |
| SCHEMBL11212265 | 0.87 | CA12 (0.40) | PKMKDM4EALDH1A1GAAKMT2A | |
| SCHEMBL7241661 | 0.83 | ALDH1A1 (0.51) | MT-CO2PTGS2PTGS1ALDH1A1GAA | |
| SCHEMBL3314391 | 0.83 | MT-CO2 (0.50) | MT-CO2PTGS2PTGS1ALDH1A1CA1 | |
| SCHEMBL11214616 | 0.81 | MT-CO2 (0.40) | MT-CO2PTGS2PTGS1GAAKMT2A | |
| SCHEMBL490875 | 0.78 | TSHR (0.59) | MT-CO2GAALMNACYP3A4 | |
| SCHEMBL11216724 | 0.78 | ALDH1A1 (0.58) | MT-CO2PTGS2PTGS1PKMKDM4E | |
| SCHEMBL31430560 | 0.78 | ALDH1A1 (0.58) | MT-CO2PTGS2PTGS1PKMKDM4E | |
| SCHEMBL5022505 | 0.77 | CYP2C19 (0.54) | MT-CO2PTGS2PTGS1ALDH1A1KMT2A | |
| SCHEMBL31409463 | 0.77 | CYP2C19 (0.54) | MT-CO2PTGS2PTGS1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0081321-A1 | 2-Aminophenol derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1983-06-15 | — | — | EP | disclosed |